Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6994763 | 0.91 | LMNA (0.37) | LMNAMEN1MAPTHTTKMT2A | |
| SCHEMBL6992106 | 0.89 | KMT2A (0.36) | LMNAMEN1MAPTHTTKMT2A | |
| SCHEMBL8874342 | 0.89 | HPGD (0.38) | LMNAMEN1MAPTHTTKMT2A | |
| SCHEMBL8862726 | 0.83 | P2RX7 (0.39) | MEN1HTTKMT2AHPGDSMN1; SMN2 | |
| SCHEMBL7958365 | 0.81 | SMN1; SMN2 (0.37) | LMNAMEN1MAPTHTTKMT2A | |
| SCHEMBL12137076 | 0.79 | L3MBTL1 (0.32) | LMNAMEN1MAPTHTTKMT2A | |
| SCHEMBL6992889 | 0.78 | TP53 (0.36) | LMNAMEN1MAPTHTTKMT2A | |
| SCHEMBL1359687 | 0.78 | CNR2 (0.37) | LMNAMEN1MAPTHTTKMT2A | |
| SCHEMBL9593911 | 0.78 | HPGD (0.36) | LMNAMEN1MAPTHTTKMT2A | |
| SCHEMBL8744778 | 0.76 | TAS1R3 (0.46) | LMNAMEN1MAPTHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0456063-B1 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1997-01-22 | — | — | EP | disclosed |
| US-5258527-A | Insecticidal, acaricidal and herbicidal 1-H-3-aryl-pyrrolidine-2,4-dione derivatives | BAYER AKTIENGESELLSCHAFT (DE) | 1993-11-02 | — | — | US | disclosed |
| EP-0456063-A2 | 1-H-3-aryl-pyrrolidin-2,4-dion-derivatives | BAYER AG (DE) | 1991-11-13 | — | — | EP | disclosed |