Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | PDE7A | Q13946 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4434523 | 0.87 | PDE7A (0.39) | ALDH1A1TP53TSHRDDB1CRBN | |
| SCHEMBL7769002 | 0.82 | KMT2A (0.42) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL8863053 | 0.82 | KMT2A (0.42) | ALDH1A1KDM4EHSD17B10MEN1KMT2A | |
| SCHEMBL4428399 | 0.74 | PDE7A (0.47) | MEN1KMT2APDE7ACA2 | |
| SCHEMBL6994973 | 0.73 | PDE7A (0.42) | ALDH1A1MEN1KMT2APDE7A | |
| SCHEMBL8559348 | 0.73 | PDE7A (0.45) | KMT2ARAB9APDE7A | |
| SCHEMBL6994685 | 0.72 | TDP1 (0.38) | ALDH1A1TP53KDM4EHSD17B10TSHR | |
| SCHEMBL8559775 | 0.71 | TSHR (0.38) | ALDH1A1TSHRRAB9ASMN1; SMN2PDE7A | |
| SCHEMBL1721097 | 0.71 | MAPT (0.35) | ALDH1A1KMT2ARAB9ASMN1; SMN2PLA2G7 | |
| SCHEMBL6767166 | 0.70 | ALDH1A1 (0.36) | ALDH1A1HSD17B10MEN1KMT2ADDB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0754175-B1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2003-01-29 | — | — | EP | disclosed |
| US-6172255-B1 | INSECTICIDES; MITICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 2001-01-09 | — | — | US | disclosed |
| US-5830826-A | Alkoxy-alkyl-substituted 1H-3-aryl-pyrrolidine-2, 4-diones used as herbicicides and pesticides | BAYER AKTIENGESELLSCHAFT (DE) | 1998-11-03 | — | — | US | disclosed |
| WO-1995026954-A1 | ALKOXY-ALKYL-SUBSTITUTED 1-H-3-ARYL-PYRROLIDINE-2,4-DIONES USED AS HERBICIDES AND PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-12 | — | — | WO | disclosed |