Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | PDE7A | Q13946 | 4/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.35 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8863053 | 1.00 | KMT2A (0.42) | KMT2ANPC1RAB9APDE7APOLB | |
| SCHEMBL6767166 | 0.86 | ALDH1A1 (0.36) | KMT2ANPC1RAB9APOLBUSP2 | |
| SCHEMBL8906325 | 0.86 | THRB (0.43) | KMT2APDE7ALMNAMEN1ALDH1A1 | |
| SCHEMBL8559348 | 0.86 | PDE7A (0.45) | KMT2ANPC1RAB9APDE7APOLB | |
| SCHEMBL6992901 | 0.82 | ALDH1A1 (0.37) | KMT2ARAB9APDE7AMEN1ALDH1A1 | |
| SCHEMBL8652013 | 0.82 | KMT2A (0.40) | KMT2ANPC1RAB9APDE7APOLB | |
| SCHEMBL8645554 | 0.81 | KMT2A (0.38) | KMT2ANPC1RAB9APDE7APOLB | |
| SCHEMBL12496757 | 0.76 | PDE7A (0.45) | PDE7AALDH1A1HTT | |
| SCHEMBL7781016 | 0.76 | DDB1 (0.36) | KMT2ALMNAMEN1ALDH1A1HPGD | |
| SCHEMBL2889210 | 0.76 | KMT2A (0.41) | KMT2ANPC1RAB9APDE7APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-6271537-A | — | — | None | — | — | JP | disclosed |
| EP-0613884-B1 | Dialkyl-1-H-3(2,4-dimethylphenyl)-pyrrolidin-2,4-diones, their preparation and their use as parasiticides and herbicides | BAYER AG (DE) | 2001-06-20 | — | — | EP | disclosed |
| US-5602078-A | POSSESS HERBICIDAL AND PESTICIDAL ACTIVITY | BAYER AKTIENGESELLSCHAFT (DE) | 1997-02-11 | — | — | US | disclosed |
| US-5504057-A | HERBICIDES; PESTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-02 | — | — | US | disclosed |
| JP-H06271537-A | DIALKYL-1-H-3-(2,4-DIMETHYLPHENYL)-PYRROLIDINE-2,4-DIONES, THEIR PREPARATION AND THEIR USE | BAYER AG | 1994-09-27 | — | — | JP | disclosed |
| EP-0613884-A2 | Dialkyl-1-H-3(2,4-dimethylphenyl)-pyrrolidin-2,4-diones, their preparation and their use as parasiticides and herbicides | BAYER AG (DE) | 1994-09-07 | — | — | EP | disclosed |