Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1737797 | 0.80 | CFD (0.53) | KDM4ELMNAALDH1A1POLBHPGD | |
| SCHEMBL5759353 | 0.80 | KMT2A (0.40) | KDM4ELMNAALDH1A1POLBHPGD | |
| SCHEMBL27548979 | 0.79 | TSHR (0.51) | KDM4ELMNAALDH1A1HPGDNPSR1 | |
| SCHEMBL2569698 | 0.77 | ALDH1A1 (0.48) | KDM4ELMNAALDH1A1POLBHPGD | |
| SCHEMBL25226665 | 0.76 | DGAT1 (0.40) | LMNAALDH1A1POLBHPGDNPSR1 | |
| SCHEMBL20660752 | 0.76 | ALDH1A1 (0.47) | KDM4ELMNAALDH1A1POLBHPGD | |
| SCHEMBL5929563 | 0.76 | ACHE (0.50) | KDM4ELMNAALDH1A1POLBHPGD | |
| SCHEMBL28320341 | 0.75 | ALDH1A1 (0.46) | KDM4ELMNAALDH1A1POLBHPGD | |
| SCHEMBL18348326 | 0.74 | KDM4E (0.42) | KDM4ELMNAALDH1A1POLBHPGD | |
| SCHEMBL259717 | 0.74 | NPSR1 (0.46) | KDM4ELMNAALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1292593-A2 | 2-(3,5-DISUBSTITUTED-4-PYRIDYL)-4-(THIENYL, THIAZOLYL OR ARYLPHENYL)-1,3-OXAZOLINE COMPOUNDS | Dow AgroSciences LLC (US) | 2003-03-19 | — | — | EP | disclosed |
| WO-2001098296-A2 | 2-(3,5-DISUBSTITUTED-4-PYRIDYL)-4-(THIENYL, THIAZOLYL OR ARYLPHENYL)-1,3-OXAZOLINE COMPOUNDS | DOW AGROSCIENCES LLC (US) | 2001-12-27 | — | — | WO | disclosed |