Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5929563 | 0.85 | ACHE (0.50) | ALDH1A1HPGDNPSR1POLBLMNA | |
| SCHEMBL28319236 | 0.81 | MRGPRX4 (0.46) | ALDH1A1NPSR1LMNASMN1; SMN2KMT2A | |
| SCHEMBL28190464 | 0.80 | CYP1A2 (0.55) | ALDH1A1HPGDNPSR1POLBLMNA | |
| SCHEMBL2569698 | 0.79 | ALDH1A1 (0.48) | ALDH1A1HPGDNPSR1POLBLMNA | |
| SCHEMBL1737797 | 0.79 | CFD (0.53) | ALDH1A1HPGDNPSR1POLBLMNA | |
| SCHEMBL7911474 | 0.78 | ALOX15 (0.53) | ALDH1A1HPGDNPSR1POLBKMT2A | |
| SCHEMBL27832701 | 0.75 | TDP1 (0.55) | NPSR1SMN1; SMN2KDM4ETDP1L3MBTL1 | |
| SCHEMBL20660752 | 0.75 | ALDH1A1 (0.47) | ALDH1A1HPGDNPSR1POLBLMNA | |
| SCHEMBL6992953 | 0.75 | KDM4E (0.44) | ALDH1A1HPGDNPSR1POLBLMNA | |
| SCHEMBL9416809 | 0.74 | TSHR (0.49) | ALDH1A1HPGDNPSR1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110143932-A | Piperazinone derivs and preparation method thereof, inhibitor and the method for preventing and treating root parasitism weeds | 南开大学 | 2019-08-20 | — | — | CN | disclosed |