Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6992847 | 0.88 | ELANE (0.43) | ELANECYP2C19ALDH1A1KDM4EPKM | |
| SCHEMBL6993818 | 0.85 | ELANE (0.43) | ELANECYP2C19ALDH1A1MAPTMEN1 | |
| SCHEMBL7507444 | 0.84 | ELANE (0.45) | ELANECYP2C19ALDH1A1MAPTMEN1 | |
| SCHEMBL6987940 | 0.84 | ELANE (0.48) | ELANECYP2C19ALDH1A1MAPTMEN1 | |
| SCHEMBL7513280 | 0.82 | ELANE (0.44) | ELANECYP2C19ALDH1A1MAPTMEN1 | |
| SCHEMBL6993400 | 0.81 | ELANE (0.42) | ELANECYP2C19ALDH1A1MAPTMEN1 | |
| SCHEMBL6993131 | 0.80 | ELANE (0.41) | ELANECYP2C19ALDH1A1MAPTMEN1 | |
| SCHEMBL7512573 | 0.80 | ELANE (0.44) | ELANECYP2C19ALDH1A1MAPTMEN1 | |
| SCHEMBL6986488 | 0.78 | GAA (0.36) | ELANEALDH1A1MAPTMEN1KMT2A | |
| Ethyl Bromo Acetate SCHEMBL7509727 | 0.77 | ALDH1A1 (0.39) | ELANECYP2C19ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345918-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002050051-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2002-06-27 | — | — | WO | disclosed |