Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 13/20 | 0.34 |
| ▸ | OPRM1 | P35372 | 11/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | TPSAB1 | Q15661 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5209729 | 0.96 | F2 (0.34) | OPRD1OPRM1OPRK1TPSAB1MEN1 | |
| Trifluoroacetic Acid SCHEMBL6996192 | 0.84 | HRH2 (0.34) | OPRD1OPRM1OPRK1TPSAB1MEN1 | |
| Trifluoroacetic Acid SCHEMBL6999298 | 0.83 | HRH2 (0.37) | OPRD1OPRM1OPRK1TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL6993355 | 0.83 | OPRM1 (0.33) | OPRD1OPRM1OPRK1TPSAB1MEN1 | |
| Trifluoroacetic Acid SCHEMBL5206361 | 0.80 | HRH2 (0.34) | OPRD1OPRM1OPRK1TPSAB1MEN1 | |
| SCHEMBL6991435 | 0.80 | F2 (0.35) | OPRD1OPRM1OPRK1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL7432339 | 0.79 | LMNA (0.37) | OPRD1OPRM1MEN1KMT2APKM | |
| Trifluoroacetic Acid SCHEMBL5205822 | 0.78 | F2 (0.34) | OPRD1OPRM1TPSAB1MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5207971 | 0.78 | HRH2 (0.37) | TPSAB1 | |
| Trifluoroacetic Acid SCHEMBL6995379 | 0.77 | TP53 (0.39) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002047762-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2002-06-20 | — | — | WO | disclosed |