Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | PKM | P14618 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | POLB | P06746 | 3/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.34 |
| ▸ | SLC12A2 | P55011 | 1/20 | 0.34 |
| ▸ | SLC12A5 | Q9H2X9 | 1/20 | 0.34 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5210132 | 0.95 | F2 (0.39) | F2RAB9AMAPTSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL5208877 | 0.85 | PIK3CA (0.35) | RAB9AMAPTSMN1; SMN2NPC1PKM | |
| Trifluoroacetic Acid SCHEMBL6999298 | 0.83 | HRH2 (0.37) | RAB9AMAPTSMN1; SMN2NPC1ALDH1A1 | |
| Trifluoroacetic Acid SCHEMBL6993355 | 0.83 | OPRM1 (0.33) | F2PKMKMT2AMEN1LMNA | |
| Trifluoroacetic Acid SCHEMBL5203620 | 0.82 | PIK3CA (0.33) | RAB9AMAPTSMN1; SMN2NPC1PKM | |
| SCHEMBL6996710 | 0.81 | NPC1 (0.43) | F2RAB9AMAPTSMN1; SMN2NPC1 | |
| Trifluoroacetic Acid SCHEMBL6996192 | 0.81 | HRH2 (0.34) | RAB9AMAPTPKMALDH1A1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5208291 | 0.80 | MAPT (0.33) | F2RAB9AMAPTSMN1; SMN2NPC1 | |
| Trifluoroacetic Acid SCHEMBL6994655 | 0.80 | OPRD1 (0.34) | PKMKMT2AMEN1OPRM1OPRD1 | |
| SCHEMBL6993286 | 0.80 | NPC1 (0.37) | F2RAB9AMAPTSMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1343561-A1 | SERINE PROTEASE INHIBITORS | Tularik Limited (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002047762-A1 | SERINE PROTEASE INHIBITORS | TULARIK LIMITED (GB) | 2002-06-20 | — | — | WO | disclosed |