Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995933 | 1.00 | FNTA (0.77) | FNTAFNTB | |
| SCHEMBL6995404 | 0.87 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL6995401 | 0.87 | FNTA (1.00) | FNTAFNTB | |
| SCHEMBL6995938 | 0.85 | FNTA (0.57) | FNTAFNTB | |
| SCHEMBL9207250 | 0.80 | HRH1 (0.75) | FNTAFNTB | |
| SCHEMBL6998702 | 0.79 | FNTA (0.61) | FNTAFNTB | |
| SCHEMBL6998698 | 0.79 | FNTA (0.61) | FNTAFNTB | |
| SCHEMBL9387368 | 0.78 | FNTA (0.82) | FNTAFNTB | |
| SCHEMBL9373907 | 0.75 | PTAFR (0.74) | FNTAFNTB | |
| SCHEMBL9208366 | 0.75 | FNTA (0.65) | FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021448-B1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6130229-A | Tricyclic compounds having activity as RAS-FPT inhibitors | SCHERING CORPORATION (US) | 2000-10-10 | — | — | US | disclosed |
| EP-1021448-A1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORPORATION (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998015556-A1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORPORATION (US) | 1998-04-16 | — | — | WO | disclosed |