Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 18/20 | 0.57 |
| ▸ | FNTB | P49356 | 18/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.49 |
| ▸ | SLC6A15 | Q9H2J7 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6995407 | 0.86 | FNTA (0.75) | FNTAFNTBHRH1SLC6A15 | |
| SCHEMBL6995933 | 0.85 | FNTA (0.77) | FNTAFNTB | |
| SCHEMBL6995930 | 0.85 | FNTA (0.77) | FNTAFNTB | |
| SCHEMBL6998698 | 0.83 | FNTA (0.61) | FNTAFNTBHRH1SLC6A15 | |
| SCHEMBL6998702 | 0.83 | FNTA (0.61) | FNTAFNTBHRH1SLC6A15 | |
| SCHEMBL9207250 | 0.79 | HRH1 (0.75) | FNTAFNTBHRH1 | |
| SCHEMBL9387368 | 0.78 | FNTA (0.82) | FNTAFNTBHRH1SLC6A15 | |
| SCHEMBL9373907 | 0.75 | PTAFR (0.74) | FNTAFNTBHRH1SLC6A15 | |
| SCHEMBL9208366 | 0.74 | FNTA (0.65) | FNTAFNTBHRH1SLC6A15 | |
| SCHEMBL6992437 | 0.73 | SLC6A15 (0.77) | FNTAFNTBHRH1SLC6A15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1021448-B1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORP (US) | 2003-05-02 | — | — | EP | disclosed |
| US-6130229-A | Tricyclic compounds having activity as RAS-FPT inhibitors | SCHERING CORPORATION (US) | 2000-10-10 | — | — | US | disclosed |
| EP-1021448-A1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORPORATION (US) | 2000-07-26 | — | — | EP | disclosed |
| WO-1998015556-A1 | TRICYCLIC COMPOUNDS HAVING ACTIVITY AS Ras-FPT INHIBITORS | SCHERING CORPORATION (US) | 1998-04-16 | — | — | WO | disclosed |