Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.52 |
| ▸ | CCR1 | P32246 | 3/20 | 0.52 |
| ▸ | CCR5 | P51681 | 3/20 | 0.52 |
| ▸ | CCR8 | P51685 | 3/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | MMP2 | P08253 | 2/20 | 0.52 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | GMNN | O75496 | 1/20 | 0.52 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | MMP9 | P14780 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.52 |
| ▸ | MMP8 | P22894 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10923588 | 0.92 | LMNA (0.78) | LMNACYP3A4KDM4EMAPTCCR1 | |
| SCHEMBL6513577 | 0.88 | LMNA (1.00) | LMNACYP3A4KDM4EMAPTCCR1 | |
| SCHEMBL8313 | 0.88 | LMNA (1.00) | LMNACYP3A4KDM4EMAPTCCR1 | |
| SCHEMBL7142651 | 0.86 | LMNA (0.96) | LMNACYP3A4KDM4EMAPTCCR1 | |
| SCHEMBL15788918 | 0.86 | LMNA (0.96) | LMNACYP3A4KDM4EMAPTCCR1 | |
| SCHEMBL7268962 | 0.86 | LMNA (0.96) | LMNACYP3A4KDM4EMAPTCCR1 | |
| SCHEMBL7722989 | 0.86 | LMNA (0.96) | LMNACYP3A4KDM4EMAPTCCR1 | |
| Iodide SCHEMBL10638043 | 0.86 | LMNA (0.96) | LMNACYP3A4KDM4EMAPTCCR1 | |
| SCHEMBL723791 | 0.86 | LMNA (0.96) | LMNACYP3A4KDM4EMAPTCCR1 | |
| SCHEMBL3885158 | 0.86 | LMNA (0.96) | LMNACYP3A4KDM4EMAPTCCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118105513-A | Conjugates comprising self-degrading groups and methods related thereto | 乐高化学生物科学股份有限公司 | 2024-05-31 | — | — | CN | claimed |
| CN-117244076-A | Conjugates comprising self-degrading groups and methods related thereto | 乐高化学生物科学股份有限公司 | 2023-12-19 | — | — | CN | claimed |
| CN-112451682-A | Conjugates comprising self-degrading groups and methods relating thereto | 乐高化学生物科学股份有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-112135638-A | Antibody-drug conjugates comprising anti-human DLK1 antibodies and uses thereof | 乐高化学生物科学股份有限公司 | 2020-12-25 | — | — | CN | claimed |
| JP-54128599-A | — | — | None | — | — | JP | disclosed |
| JP-54128567-A | — | — | None | — | — | JP | disclosed |
| CN-119816519-A | Anti-ROR 1 antibodies, bispecific antibodies comprising same and uses thereof | ABL生物公司 | 2025-04-11 | — | — | CN | disclosed |
| CN-114230664-B | Anti-C10 ORF54 antibodies and uses thereof | 皮埃尔法布雷医药公司 | 2025-01-03 | — | — | CN | disclosed |
| CN-119137157-A | Anti-Ly 6E antibodies, immunoconjugates and uses thereof | 基因泰克公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118105513-A | Conjugates comprising self-degrading groups and methods related thereto | 乐高化学生物科学股份有限公司 | 2024-05-31 | — | — | CN | disclosed |
| CN-113195542-B | CD 30-binding moieties, chimeric antigen receptors and uses thereof | 南京传奇生物科技有限公司 | 2024-05-24 | — | — | CN | disclosed |
| US-20240108745-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | MEDILINK THERAPEUTICS (SUZHOU) CO., LTD. (CN) | 2024-04-04 | — | — | US | disclosed |
| US-4354973-A | SEDATIVES AND ANXIOLYTICS | HOFFMANN-LA ROCHE INC. (US) | 1982-10-19 | — | — | US | disclosed |
| US-4354973-A | SEDATIVES AND ANXIOLYTICS | HOFFMANN-LA ROCHE INC. (US) | 1982-10-19 | — | — | US | disclosed |
| EP-0045519-A2 | Pyrrolo-(3,4-d)-benzapines, process and intermediates for their preparation and pharmaceutical compositions containing them | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-02-10 | — | — | EP | disclosed |
| JP-S54128599-A | PYRROLOBENZAZEPIN DERIVATIVE | TEIJIN LTD | 1979-10-05 | — | — | JP | disclosed |
| JP-S54128567-A | 1-SUBSTITUTED-4-ACYL-2-PYRROLECARBOXYLIC ACID DERIVATIVE | TEIJIN LTD | 1979-10-05 | — | — | JP | disclosed |
| US-4148903-A | Antipsychotic, antiserotonin and antihistaminic pyrrolo[2,1-b][3]benzazepines | MERCK & CO., INC. (US) | 1979-04-10 | — | — | US | disclosed |
| EP-0000716-A2 | Pyrrolo(2,1-b)(3)benzazepine derivatives, process for their preparation and pharmaceutical compositions containing them | MERCK & CO. INC. (US) | 1979-02-21 | — | — | EP | disclosed |
| US-4112112-A | Pyrrolo[2,1-b] [3]benzazepines useful for producing a skeletal muscle relaxing or tranquilizing effect | MERCK & CO., INC. (US) | 1978-09-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240108745-A1 | BIOACTIVE SUBSTANCE CONJUGATE, PREPARATION METHOD THEREFOR AND USE THEREOF | CTSL, VIP, FURIN | LMNA 182/4885CYP3A4 1735/4885KDM4E 4097/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.