Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.42 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MMP13 | P45452 | 1/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | FABP4 | P15090 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | PNP | P00491 | 1/20 | 0.36 |
| ▸ | FABP3 | P05413 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003073 | 0.70 | PDE1B (0.36) | TYMSLMNAMAPTMEN1KMT2A | |
| SCHEMBL7003301 | 0.67 | ADORA2A (0.35) | TYMSLMNAALDH1A1MAPTMEN1 | |
| SCHEMBL7969932 | 0.66 | MTNR1A (0.76) | TYMSMTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL34413 | 0.65 | IDO1 (0.67) | ALDH1A1HTTCYP3A4SMN1; SMN2 | |
| SCHEMBL1958423 | 0.64 | GAA (0.59) | TYMSMTNR1AMTNR1BALDH1A1MAPT | |
| SCHEMBL8581842 | 0.64 | KMT2A (0.70) | ABL1RIN1MTNR1AMTNR1BALDH1A1 | |
| Hydrochloric Acid SCHEMBL28912134 | 0.63 | IDO1 (0.68) | ALDH1A1HTTCYP3A4SMN1; SMN2 | |
| Methoxymethane SCHEMBL28823290 | 0.63 | IDO1 (0.64) | ALDH1A1HTTCYP3A4SMN1; SMN2 | |
| Potassium SCHEMBL1477050 | 0.63 | IDO1 (0.64) | ALDH1A1HTTCYP3A4SMN1; SMN2 | |
| Bromide SCHEMBL28558295 | 0.63 | IDO1 (0.64) | ALDH1A1HTTCYP3A4SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1087973-B1 | IMIDAZOTRIAZOLOPYRIMIDINES USED AS A DRUG HAVING AN ADENOSINE ANTAGONIST ACTIVITY | BOEHRINGER INGELHEIM PHARMA (DE) | 2003-01-08 | — | — | EP | disclosed |
| US-6492377-B1 | Imidazotriazolopyrimidines with adenosine-antagonistic activity | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2002-12-10 | — | — | US | disclosed |
| EP-1087973-A1 | IMIDAZOTRIAZOLOPYRIMIDINES USED AS A DRUG HAVING AN ADENOSINE ANTAGONIST ACTIVITY | Boehringer Ingelheim Pharma KG (DE) | 2001-04-04 | — | — | EP | disclosed |
| WO-2000012511-A1 | IMIDAZOTRIAZOLOPYRIMIDINES | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-03-09 | — | — | WO | disclosed |
| WO-1999065912-A1 | IMIDAZOTRIAZOLOPYRIMIDINES USED AS A DRUG HAVING AN ADENOSINE ANTAGONIST ACTIVITY | BOEHRINGER INGELHEIM PHARMA KG (DE) | 1999-12-23 | — | — | WO | disclosed |