Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.34 |
| ▸ | TRPV4 | Q9HBA0 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5146719 | 0.83 | TRPV4 (0.32) | CA12CA1CA2CA7CA13 | |
| SCHEMBL4432860 | 0.83 | CA12 (0.34) | CA12CA1CA2CA7CA13 | |
| SCHEMBL1535900 | 0.80 | CA12 (0.38) | CA12CA1CA2CA7CA13 | |
| SCHEMBL29671274 | 0.80 | CA12 (0.38) | CA12CA1CA2CA7CA13 | |
| SCHEMBL27138022 | 0.75 | TRPV4 (0.39) | TRPV4 | |
| SCHEMBL30681724 | 0.75 | TRPV4 (0.39) | TRPV4 | |
| SCHEMBL4134828 | 0.75 | TRPV4 (0.39) | TRPV4 | |
| SCHEMBL1816654 | 0.75 | TRPV4 (0.40) | CA12CA1CA2CA7CA13 | |
| SCHEMBL20401479 | 0.74 | CES2 (0.40) | CA12CA1CA2CA7CA13 | |
| SCHEMBL17056174 | 0.74 | PTGS2 (0.33) | TRPV4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8318769-B2 | Substituted sulfonamide compounds | GRUENETHAL GMBH (DE) | 2012-11-27 | — | — | US | disclosed |
| US-8124624-B2 | Substituted sulfonamide compounds | GRUENENTHAL GMBH (DE) | 2012-02-28 | — | — | US | disclosed |
| US-20090264407-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
| US-20090264400-A1 | Substituted Sulfonamide Compounds | GRUENENTHAL GMBH (DE) | 2009-10-22 | — | — | US | disclosed |
| US-7414134-B2 | B1 bradykinin receptor antagonists | AMGEN INC. (US) | 2008-08-19 | — | — | US | disclosed |
| US-7365042-B2 | Pyridine-3-sulfonyl compounds as pesticidal agents | BASF AKTIENGESELLSCHAFT (DE) | 2008-04-29 | — | — | US | disclosed |
| EP-1817306-A1 | TRIAZOLES AND THEIR USE AS BRADYKININ B1 RECEPTOR ANTAGONISTS | Amgen, Inc (US) | 2007-08-15 | — | — | EP | disclosed |
| EP-1802612-A1 | NOVEL B1 BRADYKININ RECEPTOR ANTAGONISTS | Amgen, Inc (US) | 2007-07-04 | — | — | EP | disclosed |
| US-20060167264-A1 | Pyridine-3-sulfonyl compounds as pesticidal agents | BASF AKTIENGESELLSCHAFT (DE) | 2006-07-27 | — | — | US | disclosed |
| US-20060100213-A1 | Triazoles and methods of use | AMGEN INC. (US) | 2006-05-11 | — | — | US | disclosed |
| US-20060100216-A1 | Novel B1 bradykinin receptor antagonists | AMGEN INC. (US) | 2006-05-11 | — | — | US | disclosed |
| WO-2006044412-A1 | NOVEL B1 BRADYKININ RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 2006-04-27 | — | — | WO | disclosed |
| WO-2006044355-A1 | TRIAZOLES AND THEIR USE AS BRADYKININ B1 RECEPTOR ANTAGONISTS | AMGEN INC. (US) | 2006-04-27 | — | — | WO | disclosed |
| EP-1453808-B1 | PYRIDINE-3-SULFONYL COMPOUNDS AS PESTICIDAL AGENTS | BASF AG (DE) | 2006-02-01 | — | — | EP | disclosed |
| EP-1453808-A1 | PYRIDINE-3-SULFONYL COMPOUNDS AS PESTICIDAL AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2004-09-08 | — | — | EP | disclosed |
| WO-2003043990-A1 | PYRIDINE-3-SULFONYL COMPOUNDS AS PESTICIDAL AGENTS | BASF AKTIENGESELLSCHAFT (DE) | 2003-05-30 | — | — | WO | disclosed |
| EP-0306222-A2 | Benzenesulfonanilide derivatives and fungicides for agriculture and horticulture | HOKKO CHEMICAL INDUSTRY CO., LTD (JP) | 1989-03-08 | — | — | EP | disclosed |
| EP-0008958-A1 | Fluorinated benzenesulfonate diacetylenes, a composition containing a polymer derived from these monomers; the application of such compounds in time-temperature history monitoring devices | ALLIED CORPORATION (US) | 1980-03-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264407-A1 | Substituted Sulfonamide Compounds | CNR1, SUCNR1, OPRL1 | CA12 3278/4885CA1 3223/4885CA2 1864/4885 |
| US-20060167264-A1 | Pyridine-3-sulfonyl compounds as pesticidal agents | GLRX3, ACHE, DDT | CA12 4664/4885CA1 3459/4885CA2 1287/4885 |
| US-20060100213-A1 | Triazoles and methods of use | CYP3A5, CYP3A43, CYP2E1 | CA12 4075/4885CA1 3405/4885CA2 2170/4885 |
| US-20060100216-A1 | Novel B1 bradykinin receptor antagonists | BDKRB1, BDKRB2, EDNRB | CA12 3821/4885CA1 3708/4885CA2 3079/4885 |
| US-20090264400-A1 | Substituted Sulfonamide Compounds | BDKRB1, BDKRB2, TRPV1 | CA12 2157/4885CA1 1364/4885CA2 682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.