SCHEMBL699787

SCHEMBL699787

CCCC(OC)C(CCC([InH2])CC1CCN(Cc2ccccc2)CC1)OC

nearest known ligand 0.48

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CCR3 P51677 1/20 0.46
ACHE P22303 3/20 0.44
BACE1 P56817 2/20 0.43
BCHE P06276 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL4842406 0.99 CCR3 (0.45) CCR3ACHEBACE1BCHE
SCHEMBL4206936 0.90 ACHE (0.46) CCR3ACHE
Hydrochloric Acid SCHEMBL4203851 0.89 ACHE (0.46) CCR3ACHEBCHE
SCHEMBL4209827 0.88 ACHE (0.45) CCR3ACHE
Hydrochloric Acid SCHEMBL4207910 0.87 ACHE (0.44) CCR3ACHEBCHE
SCHEMBL4203807 0.78 ACHE (0.44) CCR3ACHE
SCHEMBL12520345 0.78 ACHE (0.31) ACHE
SCHEMBL3849440 0.78 ACHE (0.42) ACHEBACE1BCHE
SCHEMBL4206058 0.77 ACHE (0.43) CCR3ACHE
SCHEMBL20214251 0.76 CCR3 (0.59) CCR3ACHEBACE1BCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1841739-B1 PROCESS FOR PRODUCING 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL] PIPERIDINE OR SALT THEREOF VIA NOVEL INTERMEDIATE JUBILANT ORGANOSYS LTD (IN) 2013-02-20 EP claimed
US-8124783-B2 Process for producing 1-benzyl-4-[5,6-dimethoxy-1-indanon-2-yl)methyl] piperidine or its salt thereof via novel intermediate JUBILANT ORGANOSYS LIMITED (IN) 2012-02-28 US claimed
US-20090137812-A1 PROCESS FOR PRODUCING 1-BENZYL-4-[5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE JUBILANT ORGANOSYS LIMITED (IN) 2009-05-28 US claimed
EP-1841739-A4 PROCESS FOR PRODUCING 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON2-YL)METHYL] PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE JUBILANT ORGANOSYS LTD (IN) 2008-10-01 EP claimed
EP-1841739-A1 PROCESS FOR PRODUCING 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON2-YL)METHYL] PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE Jubilant Organosys Limited (IN) 2007-10-10 EP claimed
WO-2006070396-A1 PROCESS FOR PRODUCING 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON­2-YL)METHYL] PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE JUBILANT ORGANOSYS LIMITED (IN) 2006-07-06 WO claimed
EP-1654230-A1 PREPARATION OF INTERMEDIATES FOR ACETYL CHOLINESTERASE INHIBITORS Hetero Drugs Limited (IN) 2006-05-10 EP claimed
US-20060041140-A1 5,6-dimethoxy-2-(4-pyridyl)methyl-1-indanone is hydrogenated using platinum oxide catalyst in the presence of hydrochloric acid under a pressure of 2 bars to give 4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride HETERO DRUGS LIMITED (IN) 2006-02-23 US claimed
WO-2005076749-A2 A NOVEL PROCESS FOR THE PREPARATION OF 1-BENZYL-4-[(5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE JUBILANT ORGANOSYS LIMITED (IN) 2005-08-25 WO claimed
WO-2005003092-A1 PREPARATION OF INTERMEDIATES FOR ACETYL CHOLINESTERASE INHIBITORS HETERO DRUGS LIMITED (IN) 2005-01-13 WO claimed
WO-1998056250-A1 METHOD FOR REDUCING SIDE EFFECTS ALCON LABORATORIES, INC. (US) 1998-12-17 WO claimed
WO-1998056249-A1 METHOD FOR ENHANCING THE ACTIVITY OF GLAUCOMA DRUGS ALCON LABORATORIES, INC. (US) 1998-12-17 WO claimed
WO-1998056379-A1 COMPOSITIONS AND METHODS FOR TREATING GLAUCOMA ALCON LABORATORIES, INC. (US) 1998-12-17 WO claimed
WO-1998056380-A1 METHOD TO REVERSE MYDRIASIS ALCON LABORATORIES, INC. (US) 1998-12-17 WO claimed
EP-4413977-A1 METHOD FOR PREPARING MICROPARTICLES CONTAINING POORLY SOLUBLE DRUGS Inventage Lab Inc. (KR) 2024-08-14 EP disclosed
CN-118234488-A Process for producing microparticles containing poorly soluble drug 创技公司株式会社 2024-06-21 CN disclosed
US-20240180896-A1 METHOD FOR PREPARING MICROPARTICLES CONTAINING POORLY SOLUBLE DRUGS INVENTAGE LAB INC. (KR) 2024-06-06 US disclosed
WO-1998056250-A1 METHOD FOR REDUCING SIDE EFFECTS ALCON LABORATORIES, INC. (US) 1998-12-17 WO disclosed
WO-1998056249-A1 METHOD FOR ENHANCING THE ACTIVITY OF GLAUCOMA DRUGS ALCON LABORATORIES, INC. (US) 1998-12-17 WO disclosed
WO-1998048785-A2 ALLELIC POLYGENE DIAGNOSIS OF REWARD DEFICIENCY SYNDROME AND TREATMENT KENNETH BLUM, INC. (US) 1998-11-05 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090137812-A1 PROCESS FOR PRODUCING 1-BENZYL-4-[5,6-DIMETHOXY-1-INDANON-2-YL)METHYL]PIPERIDINE OR ITS SALT THEREOF VIA NOVEL INTERMEDIATE TET2, DHPS, AZI2 CCR3 4746/4885ACHE 2994/4885BACE1 2856/4885
US-20240180896-A1 METHOD FOR PREPARING MICROPARTICLES CONTAINING POORLY SOLUBLE DRUGS CHMP4B, GP6, ALB CCR3 2467/4885ACHE 3367/4885BACE1 4388/4885
US-20060041140-A1 5,6-dimethoxy-2-(4-pyridyl)methyl-1-indanone is hydrogenated using platinum oxide catalyst in the presence of hydrochloric acid under a pressure of 2 bars to give 4-[(5,6-dimethoxy-1-indanon)-2-yl]methylpiperidine hydrochloride ACHE, IDH2, IMPDH2 CCR3 4712/4885ACHE 1/4885BACE1 431/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.