Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.45 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.45 |
| ▸ | HTR2C | P28335 | 2/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.45 |
| ▸ | DRD1 | P21728 | 7/20 | 0.44 |
| ▸ | PARP1 | P09874 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998213 | 1.00 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CHTR2CSLC6A3 | |
| SCHEMBL6998208 | 1.00 | ADRA2A (0.45) | ADRA2AADRA2BADRA2CHTR2CSLC6A3 | |
| SCHEMBL6995341 | 0.87 | ACHE (0.48) | — | |
| SCHEMBL6995343 | 0.87 | ACHE (0.48) | — | |
| SCHEMBL6995337 | 0.87 | ACHE (0.48) | — | |
| SCHEMBL6994578 | 0.85 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CHTR2CSLC6A3 | |
| SCHEMBL6994580 | 0.85 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CHTR2CSLC6A3 | |
| SCHEMBL6994586 | 0.85 | ADRA2A (0.43) | ADRA2AADRA2BADRA2CHTR2CSLC6A3 | |
| SCHEMBL6999335 | 0.85 | HTR1A (0.43) | ADRA2AADRA2BADRA2CHTR2CSLC6A3 | |
| SCHEMBL6999331 | 0.85 | HTR1A (0.43) | ADRA2AADRA2BADRA2CHTR2CSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015446-B1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | AVENTIS PHARMA INC (US) | 2003-04-02 | — | — | EP | disclosed |
| EP-1015446-A1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | Aventis Pharmaceuticals Inc. (US) | 2000-07-05 | — | — | EP | disclosed |
| US-6004982-A | SIDE EFFECT REDUCTION; SCHIZOPHRENIA | HOECHST MARION ROUSSEL, INC. (US) | 1999-12-21 | — | — | US | disclosed |
| WO-1998034933-A1 | (4-PIPERIDINYL)-1H-2-BENZOPYRAN DERIVATIVES USEFUL AS ANTIPSYCHOTIC AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1998-08-13 | — | — | WO | disclosed |