Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.45 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | PRKDC | P78527 | 1/20 | 0.43 |
| ▸ | FGB | P02675 | 1/20 | 0.43 |
| ▸ | NCF1 | P14598 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | CRHBP | P24387 | 2/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70655 | 0.87 | AKR1C3 (0.49) | AKR1C3ALOX15HSD17B10ADRB1SLC6A5 | |
| SCHEMBL1450530 | 0.84 | AKR1C3 (0.68) | AKR1C3ALOX15HSD17B10ADRB1SLC6A5 | |
| Ammonia Solution, Strong SCHEMBL28721079 | 0.82 | AKR1C3 (0.66) | AKR1C3ALOX15HSD17B10ADRB1SLC6A5 | |
| Boric Acid SCHEMBL6314068 | 0.78 | AKR1C3 (0.65) | AKR1C3ALOX15HSD17B10ADRB1SLC6A5 | |
| SCHEMBL3436629 | 0.78 | AKR1C3 (0.60) | AKR1C3ALOX15HSD17B10ADRB1SLC6A5 | |
| SCHEMBL15479698 | 0.74 | LMNA (0.65) | ALOX15HSD17B10ADRB1L3MBTL1LMNA | |
| SCHEMBL881474 | 0.72 | LMNA (0.61) | ALOX15HSD17B10ADRB1L3MBTL1LMNA | |
| SCHEMBL27432567 | 0.72 | L3MBTL1 (0.50) | L3MBTL1FGBLMNAPOLB | |
| SCHEMBL3436474 | 0.72 | AKR1C3 (0.61) | AKR1C3ADRB1ALDH1A1 | |
| SCHEMBL19170774 | 0.71 | ALDH1A1 (0.51) | AKR1C3ALOX15HSD17B10HPGDL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129365-B2 | Water-soluble, fluorescent compounds for detection of potassium ions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-03-06 | — | — | US | disclosed |
| US-20080311041-A1 | Water-Soluble, Fluorescent Compounds for Detection of Potassium Ions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311041-A1 | Water-Soluble, Fluorescent Compounds for Detection of Potassium Ions | TACR2, KCNJ8, TAC3 | AKR1C3 304/4885ALOX15 3768/4885HSD17B10 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.