Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.44 |
| ▸ | PRKDC | P78527 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | NSD2 | O96028 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL69985 | 0.87 | AKR1C3 (0.52) | AKR1C3ALDH1A1SLC6A5PRKDCALOX15 | |
| SCHEMBL23084117 | 0.85 | PRKDC (0.47) | ALDH1A1PRKDCALOX15HSD17B10LMNA | |
| SCHEMBL23084165 | 0.81 | PRKDC (0.44) | ALDH1A1PRKDCALOX15HSD17B10LMNA | |
| SCHEMBL1450530 | 0.81 | AKR1C3 (0.68) | AKR1C3ALDH1A1SLC6A5PRKDCALOX15 | |
| SCHEMBL70658 | 0.79 | DRD2 (0.44) | AKR1C3ALDH1A1MEN1CYP1A2CYP3A4 | |
| Ammonia Solution, Strong SCHEMBL28721079 | 0.79 | AKR1C3 (0.66) | AKR1C3ALDH1A1SLC6A5PRKDCALOX15 | |
| SCHEMBL12385911 | 0.77 | ALDH1A1 (0.69) | AKR1C3ALDH1A1PRKDCLMNAL3MBTL1 | |
| Boric Acid SCHEMBL6314068 | 0.75 | AKR1C3 (0.65) | AKR1C3ALDH1A1SLC6A5PRKDCALOX15 | |
| SCHEMBL3436629 | 0.75 | AKR1C3 (0.60) | AKR1C3ALDH1A1SLC6A5PRKDCALOX15 | |
| SCHEMBL3885064 | 0.74 | KMT2A (0.53) | ALDH1A1PRKDCHSD17B10LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129365-B2 | Water-soluble, fluorescent compounds for detection of potassium ions | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2012-03-06 | — | — | US | disclosed |
| US-20080311041-A1 | Water-Soluble, Fluorescent Compounds for Detection of Potassium Ions | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2008-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080311041-A1 | Water-Soluble, Fluorescent Compounds for Detection of Potassium Ions | TACR2, KCNJ8, TAC3 | AKR1C3 304/4885ALDH1A1 3059/4885SLC6A5 144/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.