Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 2/20 | 0.46 |
| ▸ | HTR3B | O95264 | 2/20 | 0.46 |
| ▸ | HTR3A | P46098 | 2/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 2/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.40 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540274 | 0.88 | NPSR1 (0.47) | KDRKDM4EATML3MBTL1HTR3E | |
| SCHEMBL12641988 | 0.87 | HCRTR1 (0.49) | KDRKDM4EATML3MBTL1HTR3E | |
| SCHEMBL11540070 | 0.78 | NPSR1 (0.46) | KDM4EHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11542615 | 0.78 | NPSR1 (0.46) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11541055 | 0.78 | NPSR1 (0.46) | KDM4EHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL11544638 | 0.77 | THRB (0.45) | KDM4EALDH1A1MAPTPKMKMT2A | |
| SCHEMBL11538165 | 0.77 | NPSR1 (0.51) | KDM4EMAPTKMT2AMEN1POLB | |
| SCHEMBL7433737 | 0.76 | HTR3E (0.54) | KDRKDM4EATML3MBTL1HTR3E | |
| SCHEMBL11540447 | 0.76 | POLB (0.45) | KDM4EALDH1A1MAPTKMT2AMEN1 | |
| SCHEMBL11575819 | 0.76 | HTT (0.40) | KDM4EATMHTR3EHTR3BHTR3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003724-B1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | AVENTIS PHARMA GMBH (DE) | 2003-02-12 | — | — | EP | disclosed |
| EP-1003724-A1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | Aventis Pharma Deutschland GmbH (DE) | 2000-05-31 | — | — | EP | disclosed |
| WO-1997037977-A1 | SUBSTITUTED QUINOLINE DERIVATIVES WITH ANTIVIRAL ACTION | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-10-16 | — | — | WO | disclosed |