Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 10/20 | 0.51 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MITF | O75030 | 1/20 | 0.49 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.49 |
| ▸ | THRB | P10828 | 1/20 | 0.49 |
| ▸ | XBP1 | P17861 | 1/20 | 0.49 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.49 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6998936 | 0.90 | RAB9A (0.50) | RAB9ANPC1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL6999530 | 0.85 | KAT2B (0.48) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL7001161 | 0.78 | NPC1 (0.44) | RAB9ANPC1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL7001162 | 0.78 | NPC1 (0.44) | RAB9ANPC1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL7001314 | 0.77 | RAB9A (0.52) | RAB9ANPC1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL7004455 | 0.75 | ALDH1A1 (0.46) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL7001264 | 0.74 | KAT2B (0.47) | RAB9ANPC1ALDH1A1MAPTMEN1 | |
| SCHEMBL9397355 | 0.73 | RAB9A (0.76) | RAB9ANPC1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL11726417 | 0.71 | RAB9A (0.69) | RAB9ANPC1SMN1; SMN2ALDH1A1HTT | |
| SCHEMBL7000441 | 0.71 | KAT2B (0.43) | RAB9ANPC1ALDH1A1MAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602865-B1 | Pyridazino(4,5-b)(1,5)oxazepinone, -thiazepinone and -diazepinone compounds | IVAX DRUG RESEARCH INSTITUTE, LTD. (HU) | 2003-08-05 | — | — | US | disclosed |
| EP-1129097-B1 | NOVEL TYPE CONDENSED PYRIDAZINONE COMPOUNDS | GYOGYSZERKUTATO INTEZET (HU) | 2003-01-29 | — | — | EP | disclosed |