Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 5/20 | 0.46 |
| ▸ | SRD5A1 | P18405 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | TDP2 | O95551 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7400636 | 0.87 | TDP2 (0.50) | SRD5A2SRD5A1ALDH1A1TDP2TTR | |
| SCHEMBL3199131 | 0.77 | ALDH1A1 (0.47) | SRD5A2SRD5A1ALDH1A1KDM4EMAPT | |
| SCHEMBL2171782 | 0.74 | PARP10 (0.46) | SRD5A2SRD5A1TDP2PTPRC | |
| SCHEMBL5138970 | 0.74 | ALDH1A1 (0.47) | SRD5A2SRD5A1ALDH1A1TDP2KDM4E | |
| SCHEMBL4003853 | 0.72 | BAZ2B (0.54) | ALDH1A1KDM4EMAPTPOLBKMT2A | |
| SCHEMBL9639127 | 0.71 | SRD5A2 (0.47) | SRD5A2SRD5A1ALDH1A1TDP2TTR | |
| SCHEMBL1845264 | 0.70 | SRD5A2 (0.81) | SRD5A2SRD5A1ALDH1A1TTRPTPRC | |
| SCHEMBL27506 | 0.70 | SRD5A2 (0.81) | SRD5A2SRD5A1ALDH1A1TDP2TTR | |
| SCHEMBL31456551 | 0.70 | SRD5A2 (0.81) | SRD5A2SRD5A1ALDH1A1TDP2TTR | |
| SCHEMBL2543811 | 0.70 | METAP1 (0.49) | ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355886-A1 | FUSED HETEROCYCLIC COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002062764-A9 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2002-10-10 | — | — | WO | disclosed |
| WO-2002062764-A1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-15 | — | — | WO | disclosed |