Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP2 | O95551 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.42 |
| ▸ | TTR | P02766 | 2/20 | 0.42 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | SRD5A1 | P18405 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA4 | P22748 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | KDM6B | O15054 | 1/20 | 0.37 |
| ▸ | TET3 | O43151 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7001972 | 0.87 | SRD5A2 (0.46) | TDP2ALDH1A1SRD5A2TTRPTPRC | |
| SCHEMBL5138970 | 0.77 | ALDH1A1 (0.47) | TDP2ALDH1A1SRD5A2SRD5A1POLB | |
| SCHEMBL3199131 | 0.74 | ALDH1A1 (0.47) | ALDH1A1SRD5A2SRD5A1POLBKMT2A | |
| SCHEMBL30740688 | 0.70 | TDP2 (0.46) | TDP2ALDH1A1SRD5A2TTRPTPRC | |
| SCHEMBL17327530 | 0.69 | TDP2 (0.62) | TDP2ALDH1A1SRD5A2TTRPTPRC | |
| SCHEMBL7050731 | 0.69 | TTR (0.58) | TDP2ALDH1A1SRD5A2TTRPTPRC | |
| SCHEMBL15446326 | 0.69 | ALDH1A1 (0.46) | TDP2ALDH1A1SRD5A2TTRPTPRC | |
| SCHEMBL5879567 | 0.69 | TDP2 (0.61) | TDP2ALDH1A1SRD5A2TTRPTPRC | |
| SCHEMBL5067253 | 0.69 | TDP2 (0.56) | TDP2ALDH1A1SRD5A2TTRPTPRC | |
| SCHEMBL17824647 | 0.69 | CA1 (0.45) | TDP2ALDH1A1POLBMAPTCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242120-A2 | COMBINATIONS OF GROWTH FACTORS AND I:UPA OR I:MMP FOR THE TREATMENT OF DAMAGED TISSUE | Pfizer Limited (GB) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001049309-A2 | COMBINATIONS OF GROWTH FACTORS AND I: UPA OR I: MMP FOR THE TREATMENT OF DAMAGED TISSUE | PFIZER LIMITED (GB) | 2001-07-12 | — | — | WO | disclosed |