SCHEMBL7002574

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7004878	0.91	USP30 (0.42)	HTR1AKDM4EDRD2DRD3HDAC3
	Hydrochloric Acid SCHEMBL7001226	0.89	HDAC3 (0.41)	HTR1ADRD2DRD3HDAC3HDAC4
	SCHEMBL7003217	0.88	DRD2 (0.41)	HTR1AKDM4EDRD2DRD3HDAC3
	SCHEMBL7003016	0.88	THRB (0.42)	HTR1AKDM4ENAMPT
	SCHEMBL7004553	0.87	DRD2 (0.40)	HTR1ADRD2DRD3HDAC3HDAC4
	SCHEMBL7006730	0.87	KDM4E (0.44)	HTR1AKDM4EDRD2DRD3NAMPT
	SCHEMBL7005337	0.86	HTR1A (0.38)	HTR1ADRD2DRD3CDK4CCND1
	SCHEMBL7008105	0.86	MTNR1A (0.50)	HTR1ADRD2DRD3CDK4CCND1
	SCHEMBL7009570	0.86	ROCK2 (0.42)	HTR1APKMCDK4CCND1CCNE2
	SCHEMBL7005191	0.85	PARP1 (0.42)	HTR1AKDM4EPKMDRD2DRD3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.