Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | BPTF | Q12830 | 6/20 | 0.45 |
| ▸ | BRD9 | Q9H8M2 | 5/20 | 0.42 |
| ▸ | KAT2B | Q92831 | 5/20 | 0.42 |
| ▸ | BRD4 | O60885 | 5/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KAT2A | Q92830 | 1/20 | 0.37 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.37 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999530 | 0.91 | KAT2B (0.48) | ALDH1A1BPTFBRD9KAT2BBRD4 | |
| SCHEMBL7006298 | 0.89 | ALDH1A1 (0.46) | ALDH1A1BPTFBRD9KAT2BBRD4 | |
| SCHEMBL7001264 | 0.80 | KAT2B (0.47) | ALDH1A1BPTFBRD9KAT2BBRD4 | |
| SCHEMBL7003236 | 0.79 | NPBWR1 (0.41) | BPTFBRD9KAT2BRAB9ANPC1 | |
| SCHEMBL7002772 | 0.75 | RAB9A (0.51) | ALDH1A1RAB9ANPC1MAPTGAA | |
| SCHEMBL7000441 | 0.74 | KAT2B (0.43) | ALDH1A1BPTFBRD9KAT2BBRD4 | |
| SCHEMBL7014865 | 0.71 | KMT2A (0.39) | ALDH1A1GBA1RAB9ANPC1MAPT | |
| SCHEMBL7001162 | 0.70 | NPC1 (0.44) | ALDH1A1GBA1RAB9ANPC1MAPT | |
| SCHEMBL7001161 | 0.70 | NPC1 (0.44) | ALDH1A1GBA1RAB9ANPC1MAPT | |
| SCHEMBL7001314 | 0.68 | RAB9A (0.52) | ALDH1A1RAB9ANPC1MAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602865-B1 | Pyridazino(4,5-b)(1,5)oxazepinone, -thiazepinone and -diazepinone compounds | IVAX DRUG RESEARCH INSTITUTE, LTD. (HU) | 2003-08-05 | — | — | US | disclosed |
| EP-1129097-B1 | NOVEL TYPE CONDENSED PYRIDAZINONE COMPOUNDS | GYOGYSZERKUTATO INTEZET (HU) | 2003-01-29 | — | — | EP | disclosed |
| EP-1129097-A1 | NOVEL TYPE CONDENSED PYRIDAZINONE COMPOUNDS | GYOGYSZERKUTATO INTEZET KFT. (HU) | 2001-09-05 | — | — | EP | disclosed |
| WO-2000027851-A1 | NOVEL TYPE CONDENSED PYRIDAZINONE COMPOUNDS | Gyógyszerkutató Intézet Kft. (HU) | 2000-05-18 | — | — | WO | disclosed |