Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | NPC1 | O15118 | 3/20 | 0.51 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | KAT2B | Q92831 | 7/20 | 0.46 |
| ▸ | BRD4 | O60885 | 4/20 | 0.46 |
| ▸ | BRD9 | Q9H8M2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.41 |
| ▸ | BPTF | Q12830 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6999530 | 0.77 | KAT2B (0.48) | RAB9ANPC1MAPTGAAPKM | |
| SCHEMBL7001264 | 0.74 | KAT2B (0.47) | RAB9ANPC1MAPTGAAPKM | |
| SCHEMBL7004455 | 0.68 | ALDH1A1 (0.46) | RAB9ANPC1MAPTGAAPKM | |
| SCHEMBL10806799 | 0.67 | KAT2B (0.59) | RAB9AMAPTGAAPKMKAT2B | |
| SCHEMBL10711762 | 0.66 | MAPT (1.00) | RAB9ANPC1MAPTGAAPKM | |
| SCHEMBL6403389 | 0.66 | RAB9A (0.79) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL7000441 | 0.65 | KAT2B (0.43) | RAB9ANPC1MAPTGAAPKM | |
| SCHEMBL5460753 | 0.65 | ALDH1A1 (0.54) | RAB9ANPC1MEN1KMT2AALDH1A1 | |
| SCHEMBL2857154 | 0.63 | KMT2A (0.55) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL11725968 | 0.63 | KMT2A (0.68) | RAB9ANPC1MAPTGAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6602865-B1 | Pyridazino(4,5-b)(1,5)oxazepinone, -thiazepinone and -diazepinone compounds | IVAX DRUG RESEARCH INSTITUTE, LTD. (HU) | 2003-08-05 | — | — | US | disclosed |
| EP-1129097-B1 | NOVEL TYPE CONDENSED PYRIDAZINONE COMPOUNDS | GYOGYSZERKUTATO INTEZET (HU) | 2003-01-29 | — | — | EP | disclosed |