Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | BRD4 | O60885 | 2/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.39 |
| ▸ | BRD9 | Q9H8M2 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | KAT2B | Q92831 | 1/20 | 0.39 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7005436 | 0.79 | MAPT (0.38) | DAOHSD17B10KMT2AHPGDMAPT | |
| SCHEMBL7006296 | 0.78 | TP53 (0.38) | KMT2AMAPTMEN1HTTTP53 | |
| SCHEMBL7006177 | 0.78 | DAO (0.36) | DAOKMT2AALDH1A1MEN1SMN1; SMN2 | |
| SCHEMBL7006877 | 0.78 | HTR3E (0.37) | DAOHSD17B10KMT2AHPGDALDH1A1 | |
| SCHEMBL7002931 | 0.76 | KDM4E (0.46) | HSD17B10HPGDALDH1A1LMNATP53 | |
| SCHEMBL7003133 | 0.76 | CA2 (0.44) | KMT2AALDH1A1MEN1MAPK1 | |
| SCHEMBL7002892 | 0.76 | HTR2C (0.54) | HSD17B10KMT2AHPGDMAPTALDH1A1 | |
| SCHEMBL7004576 | 0.75 | SLC9A1 (0.38) | KMT2AHPGDMAPTALDH1A1MEN1 | |
| SCHEMBL7009955 | 0.74 | NPC1 (0.56) | KMT2AMEN1CREBBP | |
| SCHEMBL7006729 | 0.74 | ALOX5 (0.48) | KMT2AMEN1CA12CA9CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |