Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | BRD4 | O60885 | 5/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.38 |
| ▸ | HTR6 | P50406 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7009955 | 0.76 | NPC1 (0.56) | MAPK14L3MBTL1MAOBMEN1NPC1 | |
| SCHEMBL7003203 | 0.74 | MTNR1A (0.43) | MAPK14MAPTMAPK1MEN1NPC1 | |
| SCHEMBL7006729 | 0.74 | ALOX5 (0.48) | MAPK14L3MBTL1MAOBACHEMEN1 | |
| SCHEMBL11970494 | 0.70 | MAPK14 (0.52) | MAPK14MAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL24556370 | 0.69 | MAPK14 (0.49) | MAPK14MAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL6797552 | 0.69 | KDM4E (0.49) | MAPTTDP1L3MBTL1MAPK1CYP2C9 | |
| SCHEMBL9007487 | 0.68 | MAPT (0.80) | MAPK14MAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL15957895 | 0.67 | TP53 (0.55) | MAPK14MAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL22990508 | 0.66 | MAPK14 (0.68) | MAPK14MAPTTDP1L3MBTL1MAPK1 | |
| SCHEMBL4384374 | 0.66 | MAPK14 (0.68) | MAPK14MAPTTDP1L3MBTL1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |