Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | RAB9A | P51151 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.55 |
| ▸ | MAOB | P27338 | 4/20 | 0.49 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006729 | 0.90 | ALOX5 (0.48) | NPC1RAB9AMEN1KMT2ASRD5A2 | |
| SCHEMBL7007443 | 0.79 | MEN1 (0.51) | NPC1RAB9AMEN1KMT2ASRD5A2 | |
| SCHEMBL7002931 | 0.79 | KDM4E (0.46) | L3MBTL1 | |
| SCHEMBL7003392 | 0.76 | MAPK14 (0.48) | NPC1RAB9AMEN1KMT2AMAOB | |
| SCHEMBL1400791 | 0.76 | NPC1 (0.63) | NPC1RAB9AMEN1KMT2ASRD5A2 | |
| SCHEMBL7004499 | 0.75 | MCHR1 (0.47) | NPC1RAB9AMEN1KMT2ASRD5A2 | |
| SCHEMBL7006801 | 0.75 | MAPK14 (0.54) | NPC1MEN1KMT2AMAOBALOX5 | |
| SCHEMBL7009665 | 0.75 | ALOX5 (0.47) | NPC1RAB9AMEN1KMT2ASRD5A2 | |
| SCHEMBL7001976 | 0.74 | MCHR1 (0.47) | NPC1RAB9AMEN1KMT2ASRD5A2 | |
| SCHEMBL7003203 | 0.74 | MTNR1A (0.43) | NPC1RAB9AMEN1KMT2ASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |