Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.40 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.39 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.38 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.37 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.37 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CTSV | O60911 | 1/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003203 | 0.83 | MTNR1A (0.43) | ALDH1A1MAPTHSD17B10KDM4CSIRT2 | |
| SCHEMBL7003213 | 0.75 | NSD2 (0.50) | SRD5A2NPC1RAB9ACTSVCTSL | |
| SCHEMBL7007443 | 0.72 | MEN1 (0.51) | ALDH1A1HSD17B10SRD5A2NPC1HPGD | |
| SCHEMBL7834454 | 0.70 | POLB (0.43) | MAPTSIRT2POLBNPC1RAB9A | |
| SCHEMBL12303126 | 0.66 | MAPT (0.57) | ALDH1A1MAPTPOLBNPC1HPGD | |
| SCHEMBL7283929 | 0.66 | POLB (0.52) | ALDH1A1MAPTHSD17B10KDM4CSIRT2 | |
| SCHEMBL4047377 | 0.66 | ADORA3 (0.43) | ALDH1A1MAPTHSD17B10KDM4CSIRT2 | |
| SCHEMBL24567041 | 0.65 | MAPK14 (0.49) | KDM4CPOLBNSD2ABL1PPARG | |
| SCHEMBL17912878 | 0.65 | MAPT (0.66) | MAPTL3MBTL1 | |
| SCHEMBL3897534 | 0.65 | POLB (0.43) | MAPTSIRT2POLBNPC1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |