Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 1/20 | 0.50 |
| ▸ | ABL1 | P00519 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.50 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.49 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 5/20 | 0.45 |
| ▸ | MAOA | P21397 | 4/20 | 0.45 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7003213 | 0.90 | NSD2 (0.50) | MEN1NPC1KMT2ARAB9ASRD5A2 | |
| SCHEMBL7009955 | 0.79 | NPC1 (0.56) | MEN1NPC1KMT2ARAB9ASRD5A2 | |
| SCHEMBL15903599 | 0.77 | IP6K1 (0.54) | MEN1NPC1KMT2ARAB9ASRD5A2 | |
| SCHEMBL4751214 | 0.73 | PARP1 (0.41) | MEN1KMT2ACHEK1KDM4EALDH1A1 | |
| SCHEMBL13711924 | 0.72 | PARP1 (0.61) | MAOBMAOACHEK1MAPK14 | |
| SCHEMBL7004603 | 0.72 | ALDH1A1 (0.40) | MEN1NPC1KMT2ARAB9ASRD5A2 | |
| SCHEMBL7006729 | 0.69 | ALOX5 (0.48) | MEN1NPC1KMT2ARAB9ASRD5A2 | |
| SCHEMBL1400791 | 0.69 | NPC1 (0.63) | MEN1NPC1KMT2ARAB9ASRD5A2 | |
| SCHEMBL3979896 | 0.69 | ROCK1 (0.58) | MEN1NPC1KMT2ARAB9ASRD5A2 | |
| SCHEMBL5483649 | 0.69 | SRD5A2 (0.57) | MEN1NPC1KMT2ARAB9ASRD5A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |