Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.32 |
| ▸ | THRA | P10827 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.31 |
| ▸ | S1PR5 | Q9H228 | 5/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 4/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006238 | 0.85 | THRB (0.31) | THRBTHRAS1PR1S1PR5 | |
| SCHEMBL7007555 | 0.82 | FFAR4 (0.34) | THRBTHRAESR1 | |
| SCHEMBL7006211 | 0.80 | THRA (0.32) | THRBTHRAESR1 | |
| SCHEMBL7003285 | 0.79 | ESR1 (0.38) | THRBESR1 | |
| SCHEMBL5236587 | 0.73 | THRB (0.34) | THRBTHRAS1PR1S1PR5TAAR1 | |
| SCHEMBL5234366 | 0.67 | ALDH1A1 (0.33) | THRBTHRA | |
| SCHEMBL5234473 | 0.66 | THRB (0.37) | THRBTHRAESR1 | |
| SCHEMBL7592050 | 0.65 | THRA (0.36) | THRBTHRA | |
| SCHEMBL5239328 | 0.65 | CNR2 (0.36) | ESR1 | |
| SCHEMBL7562047 | 0.65 | TNF (0.37) | ESR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1355886-A1 | FUSED HETEROCYCLIC COMPOUNDS | Takeda Chemical Industries, Ltd. (JP) | 2003-10-29 | — | — | EP | disclosed |
| WO-2002062764-A1 | FUSED HETEROCYCLIC COMPOUNDS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2002-08-15 | — | — | WO | disclosed |