Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNMT | P11086 | 2/20 | 0.53 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | IDO1 | P14902 | 3/20 | 0.48 |
| ▸ | TDO2 | P48775 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TACR1 | P25103 | 3/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | CTSB | P07858 | 1/20 | 0.43 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | AGXT | P21549 | 2/20 | 0.42 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.41 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.41 |
| ▸ | ACP3 | P15309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1641620 | 0.80 | SLC6A2 (0.48) | SLC6A2SLC6A4SIGMAR1TAAR1CYP3A4 | |
| SCHEMBL25517567 | 0.80 | LMNA (0.65) | PNMTSLC6A2SLC6A4IDO1TDO2 | |
| SCHEMBL7009003 | 0.79 | SLC6A4 (0.47) | SLC6A2SLC6A4IDO1TDO2SIGMAR1 | |
| SCHEMBL949577 | 0.79 | PNMT (0.62) | PNMTSLC6A2SLC6A4IDO1TDO2 | |
| SCHEMBL27666865 | 0.79 | TAAR1 (0.46) | SLC6A2SLC6A4IDO1LMNATACR1 | |
| Ammonia Solution, Strong SCHEMBL8867398 | 0.77 | PNMT (0.61) | PNMTSLC6A2SLC6A4IDO1TDO2 | |
| SCHEMBL5304517 | 0.76 | PNMT (0.54) | PNMTSLC6A2SLC6A4IDO1TDO2 | |
| SCHEMBL4668971 | 0.76 | PNMT (0.69) | PNMTIDO1LMNASIGMAR1TAAR1 | |
| SCHEMBL22394811 | 0.75 | MEN1 (0.56) | PNMTSLC6A2SLC6A4IDO1TDO2 | |
| SCHEMBL11824738 | 0.74 | PNMT (0.56) | PNMTSLC6A2SLC6A4IDO1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1267906-A1 | LACTAMS AS INHIBITORS OF A-BETA PROTEIN PRODUCTION | Bristol-Myers Squibb Pharma Company (US) | 2003-01-02 | — | — | EP | claimed |
| WO-2001072324-A1 | LACTAMS AS INHIBITORS OF A-BETA PROTEIN PRODUCTION | BRISTOL-MYERS SQUIBB PHARMA COMPANY (US) | 2001-10-04 | — | — | WO | claimed |