Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.48 |
| ▸ | CCR2 | P41597 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 6/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.43 |
| ▸ | F10 | P00742 | 2/20 | 0.42 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7006463 | 0.89 | CCR2 (0.60) | HPGDHSD17B10TNFRSF1ACCR2LMNA | |
| SCHEMBL7097677 | 0.88 | HPGD (0.52) | HPGDHSD17B10TNFRSF1ACCR2LMNA | |
| SCHEMBL5622779 | 0.80 | CCR2 (0.47) | HPGDHSD17B10CCR2LMNAMTNR1B | |
| SCHEMBL6775247 | 0.80 | CCR2 (0.65) | CCR2MTNR1BMTNR1AF10KMT2A | |
| SCHEMBL2276664 | 0.77 | L3MBTL1 (0.52) | HPGDHSD17B10CCR2LMNAMTNR1B | |
| SCHEMBL6433700 | 0.74 | CCR2 (0.54) | HPGDCCR2LMNAMTNR1BMTNR1A | |
| SCHEMBL8299631 | 0.73 | MTNR1A (0.59) | HPGDHSD17B10CCR2MTNR1BMTNR1A | |
| SCHEMBL5624192 | 0.73 | CCR2 (0.42) | HPGDHSD17B10CCR2LMNAMTNR1B | |
| SCHEMBL699964 | 0.72 | CCR2 (0.65) | HPGDHSD17B10CCR2LMNAMTNR1B | |
| SCHEMBL31008782 | 0.71 | CCR2 (0.51) | HPGDHSD17B10CCR2LMNAMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1200439-B1 | 1,2-DIHYDRO-1-OXO-PARAZINO(1,2-A) INDOLE DERIVATIVES | NOVUSPHARMA SPA (IT) | 2003-06-25 | — | — | EP | disclosed |