Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.37 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | TEAD4 | Q15561 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 3/20 | 0.33 |
| ▸ | CES1 | P23141 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ASPH | Q12797 | 1/20 | 0.33 |
| ▸ | KDM8 | Q8N371 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.32 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.32 |
| ▸ | ALB | P02768 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.31 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.31 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8946849 | 0.86 | KEAP1 (0.35) | KEAP1NFE2L2MAPTALDH1A1CES2 | |
| SCHEMBL7811260 | 0.86 | ALDH1A1 (0.37) | KEAP1NFE2L2MAPTALDH1A1KMT2A | |
| SCHEMBL7016307 | 0.85 | KEAP1 (0.35) | KEAP1NFE2L2TAS2R14MAPTALDH1A1 | |
| SCHEMBL7012967 | 0.85 | KEAP1 (0.34) | KEAP1NFE2L2TAS2R14MAPTALDH1A1 | |
| SCHEMBL7007318 | 0.84 | ALDH1A1 (0.46) | KEAP1NFE2L2MAPTALDH1A1KMT2A | |
| SCHEMBL6648524 | 0.84 | DGAT1 (0.36) | MAPTALDH1A1CES2CES1KDM4E | |
| SCHEMBL9566698 | 0.81 | KEAP1 (0.32) | KEAP1NFE2L2MAPT | |
| SCHEMBL9566655 | 0.78 | KEAP1 (0.34) | KEAP1NFE2L2MAPTALDH1A1CES2 | |
| SCHEMBL9561822 | 0.78 | SLC6A2 (0.36) | MAPTALDH1A1KDM4ECA1CA2 | |
| SCHEMBL607945 | 0.78 | HSD17B10 (0.44) | KEAP1NFE2L2MAPTALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1827580-A | Synthesis process of 3-difluoromethoxy-2, 4, 5-trifluorobenzoic acid | DAFENG TIANSHENG PHARMACEUTICA (CN) | 2006-09-06 | — | — | CN | disclosed |
| CN-1827580-A | Synthesis process of 3-difluoromethoxy-2, 4, 5-trifluorobenzoic acid | DAFENG TIANSHENG PHARMACEUTICA (CN) | 2006-09-06 | — | — | CN | disclosed |
| CN-1827580-A | Synthesis process of 3-difluoromethoxy-2, 4, 5-trifluorobenzoic acid | DAFENG TIANSHENG PHARMACEUTICA (CN) | 2006-09-06 | — | — | CN | disclosed |
| CN-1580055-A | Quinolone carboxylic acid derivatives and their salts | XINCHUANG MEDICINE SCIENCE TEC (CN) | 2005-02-16 | — | — | CN | disclosed |
| EP-0610958-B1 | Intermediates in the preparation of 4-oxoquinoline-3-carboxylic acid derivatives | UBE INDUSTRIES (JP) | 2001-10-04 | — | — | EP | disclosed |
| EP-0878194-A1 | REMEDIES OR PREVENTIVES FOR AIDS | SANKYO COMPANY LIMITED (JP) | 1998-11-18 | — | — | EP | disclosed |
| US-5688791-A | COMPOUNDS FOR TREATMENNT OF VIRAL DISEASES SUCH AS AIDS | UBE INDUSTRIES, LTD. (JP) | 1997-11-18 | — | — | US | disclosed |
| US-5519016-A | Aryl group- or aromatic heterocyclic group-substituted aminoquinolone derivatives and anti-HIV agent | UBE INDUSTRIES, LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| US-5496951-A | 1-CYCLOPROPYL-6-FLUORO-8-FLUORINATED METHOXY COMPOUNDS INCLUDING BORON DIFLUORIDE CHELATE; CHEMICAL INTERMEDIATES AND ANTIBACTERIAL AGENTS | SANKYO COMPANY, LIMITED (JP) | 1996-03-05 | — | — | US | disclosed |
| US-5436367-A | 3, 4-difluorobenzoic acid derivatives | SANKO COMPANY, LIMITED (JP) | 1995-07-25 | — | — | US | disclosed |
| CN-1028226-C | 4-Oxoquinoline-3-carboxylic acid derivatives, their preparation and their use | UBE INDUSTRIES (JP) | 1995-04-19 | — | — | CN | disclosed |
| EP-0352123-B1 | 4-Oxoquinoline-3-carboxylic acid derivatives, their preparation and their use | UBE INDUSTRIES (JP) | 1995-01-18 | — | — | EP | disclosed |
| US-5348961-A | Antibacterial agents | SANKYO COMPANY LIMITED (JP) | 1994-09-20 | — | — | US | disclosed |
| EP-0610958-A2 | Intermediates in the preparation of 4-oxoquinoline-3-carboxylic acid derivatives | UBE INDUSTRIES, LTD. (JP) | 1994-08-17 | — | — | EP | disclosed |
| EP-0572259-A1 | Aminoquinolone derivatives as anti-HIV agents | UBE INDUSTRIES, LTD. (JP) | 1993-12-01 | — | — | EP | disclosed |
| US-5073556-A | Bactericides | SANKYO COMPANY LIMITED (JP) | 1991-12-17 | — | — | US | disclosed |
| CN-1040977-A | The preparation and the use of 4-Oxoquinoline-3-carboxylic acid derivative | UBE INDUSTRIES (JP) | 1990-04-04 | — | — | CN | disclosed |
| EP-0352123-A2 | 4-Oxoquinoline-3-carboxylic acid derivatives, their preparation and their use | UBE INDUSTRIES LIMITED (JP) | 1990-01-24 | — | — | EP | disclosed |