Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.32 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.32 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.31 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3980124 | 0.82 | ENPP2 (0.34) | ALDH1A1ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL1138975 | 0.74 | ALDH1A1 (0.42) | ALDH1A1KDM4ERECQLENPP2ORAI1 | |
| SCHEMBL2058939 | 0.73 | — | — | |
| SCHEMBL700808 | 0.73 | ALDH1A1 (0.34) | ALDH1A1KDM4ERECQLGAA | |
| SCHEMBL14703738 | 0.73 | ENPP2 (0.46) | ALDH1A1ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL7930396 | 0.73 | ENPP2 (0.41) | ALDH1A1ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL10269835 | 0.71 | GAA (0.37) | ALDH1A1KDM4EENPP2ORAI1ORAI2 | |
| SCHEMBL7784917 | 0.70 | TSHR (0.43) | ALDH1A1KDM4EENPP2ORAI1ORAI2 | |
| SCHEMBL3988450 | 0.70 | ENPP2 (0.39) | ALDH1A1ENPP2ORAI1ORAI2ORAI3 | |
| SCHEMBL16984910 | 0.70 | ENPP2 (0.39) | ALDH1A1ENPP2ORAI1ORAI2ORAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9090590-B2 | Organic compounds for electroluminescent devices | MERCK PATENT GMBH (DE) | 2015-07-28 | — | — | US | disclosed |
| US-20130053558-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2013-02-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130053558-A1 | ORGANIC COMPOUNDS FOR ELECTROLUMINESCENT DEVICES | PIEZO1, EMC1, EPCAM | ALDH1A1 62/4885KDM4E 3460/4885RECQL 2580/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.