Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAMK2D | Q13557 | 16/20 | 0.49 |
| ▸ | PRKACA | P17612 | 3/20 | 0.49 |
| ▸ | PRKACG | P22612 | 3/20 | 0.49 |
| ▸ | PRKACB | P22694 | 3/20 | 0.49 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.49 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.42 |
| ▸ | CDK9 | P50750 | 1/20 | 0.42 |
| ▸ | CDK4 | P11802 | 2/20 | 0.41 |
| ▸ | CCND1 | P24385 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7004902 | 0.93 | CAMK2D (0.56) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL6985276 | 0.88 | CAMK2D (0.49) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL7011017 | 0.86 | CAMK2D (0.54) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL6984540 | 0.85 | CAMK2D (0.46) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL6986094 | 0.84 | PRKACA (0.45) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| SCHEMBL7012175 | 0.81 | RPS6KB1 (0.59) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| Acetic Acid SCHEMBL7010791 | 0.79 | RPS6KB1 (0.51) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| SCHEMBL6981937 | 0.79 | CAMK2D (0.56) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| Trifluoroacetic Acid SCHEMBL6982571 | 0.78 | CCNT1 (0.44) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 | |
| SCHEMBL7007889 | 0.77 | CAMK2D (0.62) | CAMK2DPRKACAPRKACGPRKACBRPS6KB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030134886-A1 | Pharmaceutically active compounds | ASTRAZENECA AB, A SWEDISH CORPORATION | 2003-07-17 | — | — | US | disclosed |
| EP-1042317-B1 | Indole derivatives as PKC-inhiboitors | ASTRAZENECA AB (SE) | 2003-05-14 | — | — | EP | disclosed |
| US-6492409-B1 | SUCH AS 5-(1-(3-AMINOPROPYL)-3-INDOLYL)-1-(3-INDOLYL)-1,3-DIHYDROIMIDAZOL-2-ONE; PROTEIN KINASE C INHIBITORS; HIGH SOLUBILITY; REDUCED COLOR; TREATING INFLAMMATORY AND/OR IMMUNOLOGICAL DISORDERS | ASTRAZENECA AB (SE) | 2002-12-10 | — | — | US | disclosed |
| US-6337342-B1 | ARYLIMIDAZOLONE DERIVATIVES | ASTRAZENECA AB (SE) | 2002-01-08 | — | — | US | disclosed |
| EP-1042317-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | AstraZeneca AB (SE) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999032483-A1 | NEW PHARMACEUTICALLY ACTIVE COMPOUNDS | ASTRAZENECA AB (SE) | 1999-07-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030134886-A1 | Pharmaceutically active compounds | HTR3C, HTR6, CNR1 | CAMK2D 3573/4885PRKACA 3300/4885PRKACG 3599/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.