Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.30 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6850900 | 0.83 | CHRM3 (0.31) | CHRM3CHRM2CHRM1 | |
| SCHEMBL6846889 | 0.83 | CHRM2 (0.33) | CHRM3CHRM2CHRM1 | |
| SCHEMBL7009826 | 0.80 | MTNR1A (0.43) | CHRM3CHRM2CHRM1 | |
| SCHEMBL1417680 | 0.78 | PDK1 (0.34) | — | |
| SCHEMBL6849635 | 0.76 | ACHE (0.35) | ALDH1A1ACHE | |
| SCHEMBL6849628 | 0.74 | CCR2 (0.41) | MEN1KMT2AALDH1A1BCHEACHE | |
| SCHEMBL6851333 | 0.74 | CCR2 (0.41) | SMN1; SMN2MEN1KMT2ALMNABCHE | |
| SCHEMBL1417623 | 0.73 | ALDH1A1 (0.37) | SMN1; SMN2MEN1NPC1RAB9AKMT2A | |
| SCHEMBL6852753 | 0.73 | CHRM3 (0.33) | CHRM3CHRM2CHRM1 | |
| SCHEMBL6846766 | 0.73 | CHRM3 (0.33) | CHRM3CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268484-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001068652-A1 | CONDENSED IMIDAZOLES AS HISTAMINE H3 RECEPTOR LIGANDS | NOVO NORDISK A/S (DK) | 2001-09-20 | — | — | WO | disclosed |