SCHEMBL7011209

SCHEMBL7011209

Cc1cccc(Cc2nnc(C(=O)[C@@H](NC(=O)CN3C(=O)N[C@H](C(C)C)C3=O)C(C)C)o2)c1

nearest known ligand 0.57

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ELANE P08246 16/20 0.57
SMN1; SMN2 Q16637 1/20 0.40
POLB P06746 2/20 0.37
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28743196 1.00 ELANE (0.57) ELANESMN1; SMN2POLBTP53
SCHEMBL7011212 1.00 ELANE (0.57) ELANESMN1; SMN2POLBTP53
SCHEMBL27520900 0.86 ELANE (0.53) ELANESMN1; SMN2POLBTP53
SCHEMBL7202085 0.83 ELANE (0.59) ELANESMN1; SMN2
SCHEMBL27502036 0.83 ELANE (0.58) ELANESMN1; SMN2POLBTP53
SCHEMBL27561947 0.80 ELANE (0.57) ELANEPOLB
SCHEMBL7511605 0.79 ELANE (0.58) ELANESMN1; SMN2POLBTP53
SCHEMBL8495511 0.79 ELANE (0.56) ELANESMN1; SMN2
SCHEMBL3052693 0.79 ELANE (0.56) ELANESMN1; SMN2POLBTP53
SCHEMBL8492232 0.78 ELANE (0.55) ELANESMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030216324-A1 Airway mucus secretion inhibitors ONO PHARMACEUTICAL CO., LTD. (JP) 2003-11-20 US claimed
US-20030212115-A1 Remedies for inflammatory bowel diseases ONO PHARMACEUTICAL CO., LTD. (JP) 2003-11-13 US claimed
EP-1323420-A1 REMEDIES FOR INFLAMMATORY BOWEL DISEASES ONO PHARMACEUTICAL CO., LTD. (JP) 2003-07-02 EP claimed
EP-1323419-A1 AIRWAY MUCUS SECRETION INHIBITORS ONO PHARMACEUTICAL CO., LTD. (JP) 2003-07-02 EP claimed
EP-4181781-B1 BREATH-BASED THERAPEUTIC DRUG MONITORING METHOD UNIV KINDERSPITAL BEIDER BASEL (CH) 2026-05-20 EP disclosed
US-20230277125-A1 BREATH-BASED THERAPEUTIC DRUG MONITORING METHOD UNIVERSITÄTS-KINDERSPITAL BEIDER BASEL (CH) 2023-09-07 US disclosed
US-20030216324-A1 Airway mucus secretion inhibitors ONO PHARMACEUTICAL CO., LTD. (JP) 2003-11-20 US disclosed
EP-1323419-A1 AIRWAY MUCUS SECRETION INHIBITORS ONO PHARMACEUTICAL CO., LTD. (JP) 2003-07-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030212115-A1 Remedies for inflammatory bowel diseases NOS3, TPMT, NOS2 ELANE 588/4885SMN1; SMN2 3261/4885POLB 2438/4885
US-20030216324-A1 Airway mucus secretion inhibitors MUC1, CFTR, SERPINB1 ELANE 19/4885SMN1; SMN2 4823/4885POLB 3060/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.