SCHEMBL701238

SCHEMBL701238

CCC(CC)NC(=O)/C=C/c1ccc(OC)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TAS1R3 Q7RTX0 8/20 1.00
TAS1R1 Q7RTX1 8/20 1.00
SMN1; SMN2 Q16637 3/20 0.66
HDAC3 O15379 3/20 0.65
HDAC1 Q13547 3/20 0.65
HDAC2 Q92769 3/20 0.65
HDAC8 Q9BY41 3/20 0.65
HDAC6 Q9UBN7 2/20 0.65
GSK3B P49841 1/20 0.62
HDAC4 P56524 1/20 0.60
HDAC7 Q8WUI4 1/20 0.60
HDAC10 Q969S8 1/20 0.60
HDAC11 Q96DB2 1/20 0.60
HDAC9 Q9UKV0 1/20 0.60
HDAC5 Q9UQL6 1/20 0.60
CYP1A2 P05177 1/20 0.59
CYP2C19 P33261 1/20 0.59
GAA P10253 1/20 0.58
RECQL P46063 1/20 0.58
TP53 P04637 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL701239 1.00 TAS1R3 (1.00) TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1
SCHEMBL20662848 0.92 TAS1R3 (0.90) TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1
SCHEMBL702907 0.92 TAS1R3 (1.00) TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1
SCHEMBL702906 0.92 TAS1R3 (1.00) TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1
SCHEMBL10226438 0.91 TAS1R3 (0.82) TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1
SCHEMBL703477 0.89 TAS1R3 (1.00) TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1
SCHEMBL703476 0.89 TAS1R3 (1.00) TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1
SCHEMBL23470214 0.87 TAS1R3 (0.78) TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1
SCHEMBL701222 0.87 TAS1R3 (0.78) TAS1R3TAS1R1SMN1; SMN2MAPTRAB9A
SCHEMBL701223 0.87 TAS1R3 (0.78) TAS1R3TAS1R1SMN1; SMN2MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117137048-A Flavor composition, food comprising the same, and method for increasing the flavor intensity of the umami taste of food 马斯公司 2023-12-01 CN claimed
US-20250143359-A1 COMPOUNDS THAT MODULATE GPR92 RECEPTOR ACTIVITY AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2025-05-08 US disclosed
US-20250127196-A1 COMPOUNDS THAT MODULATE FATTY ACID RECEPTOR ACTIVITY AND PET FOOD PRODUCTS CONTAINING THE SAME MARS, INCORPORATED (US) 2025-04-24 US disclosed
EP-3229611-B1 COMPOUNDS THAT MODULATE FATTY ACID RECEPTOR ACTIVITY AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2025-03-26 EP disclosed
US-12207672-B2 Compounds that modulate GPR92 receptor activity and pet food products containing the same MARS, INCORPORATED (US) 2025-01-28 US disclosed
US-12207673-B2 Compounds that modulate fatty acid receptor activity and pet food products containing the same MARS, INCORPORATED (US) 2025-01-28 US disclosed
EP-4403042-A2 FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME Mars, Incorporated (US) 2024-07-24 EP disclosed
EP-3229612-B1 USE OF FLAVOR COMPOSITIONS AND PET FOOD PRODUCTS CONTAINING THE SAME MARS INC (US) 2024-06-26 EP disclosed
CN-117137048-A Flavor composition, food comprising the same, and method for increasing the flavor intensity of the umami taste of food 马斯公司 2023-12-01 CN disclosed
US-11268952-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof FIRMENICH INCORPORATED (US) 2022-03-08 US disclosed
US-7476399-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX INC. (US) 2009-01-13 US disclosed
US-7476399-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX INC. (US) 2009-01-13 US disclosed
US-7476399-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof SENOMYX INC. (US) 2009-01-13 US disclosed
US-20080085994-A1 Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli SENOMYX, INC. 2008-04-10 US disclosed
US-20080085994-A1 Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli SENOMYX, INC. 2008-04-10 US disclosed
US-20080085994-A1 Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli SENOMYX, INC. 2008-04-10 US disclosed
US-20070104709-A1 Non-naturally occurring ligand for umami taste and sweet taste receptor; enhancing response to artificial flavoring FIRMENICH INCORPORATED 2007-05-10 US disclosed
US-20070104709-A1 Non-naturally occurring ligand for umami taste and sweet taste receptor; enhancing response to artificial flavoring FIRMENICH INCORPORATED 2007-05-10 US disclosed
US-20060045953-A1 Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers SENOMYX, INC. 2006-03-02 US disclosed
US-20050084506-A1 Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products FIRMENICH INCORPORATED 2005-04-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11268952-B2 Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof TAS2R40, TAS1R2, TAS1R1 TAS1R3 5/4885TAS1R1 3/4885SMN1; SMN2 2642/4885
US-20050084506-A1 Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products TAS2R40, TAS2R4, TAS2R30 TAS1R3 17/4885TAS1R1 11/4885SMN1; SMN2 3009/4885
US-20070104709-A1 Non-naturally occurring ligand for umami taste and sweet taste receptor; enhancing response to artificial flavoring TAS1R2, TAS1R3, TAS2R30 TAS1R3 2/4885TAS1R1 4/4885SMN1; SMN2 3008/4885
US-20080085994-A1 Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli TAS1R3, TAS1R2, TAS2R30 TAS1R3 1/4885TAS1R1 4/4885SMN1; SMN2 3772/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.