Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 8/20 | 1.00 |
| ▸ | TAS1R1 | Q7RTX1 | 8/20 | 1.00 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.58 |
| ▸ | GSK3B | P49841 | 1/20 | 0.56 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.55 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.55 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.55 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.55 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.55 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | RECQL | P46063 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL702906 | 1.00 | TAS1R3 (1.00) | TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL701239 | 0.92 | TAS1R3 (1.00) | TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL701238 | 0.92 | TAS1R3 (1.00) | TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL704323 | 0.87 | TAS1R3 (0.80) | TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL704322 | 0.87 | TAS1R3 (0.80) | TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL6015465 | 0.87 | TAS1R3 (0.80) | TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL20662848 | 0.87 | TAS1R3 (0.90) | TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL10226438 | 0.86 | TAS1R3 (0.82) | TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL703477 | 0.84 | TAS1R3 (1.00) | TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL703476 | 0.84 | TAS1R3 (1.00) | TAS1R3TAS1R1SMN1; SMN2HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10352929-B2 | T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds | SENOMYX, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| EP-3431464-A2 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | Senomyx Inc. (US) | 2019-01-23 | — | — | EP | disclosed |
| US-10060909-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX, INC. (US) | 2018-08-28 | — | — | US | disclosed |
| US-20180003702-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | SENOMYX, INC. | 2018-01-04 | — | — | US | disclosed |
| US-9459250-B2 | Use of T1R3 venus flytrap region polypeptide to screen for taste modulators | SENOMYX, INC. (US) | 2016-10-04 | — | — | US | disclosed |
| US-9091686-B2 | Chimeric T1R taste receptor polypeptides and nucleic acid sequences encoding and cell lines that express said chimeric T1R polypeptides | SENOMYX, INC. (US) | 2015-07-28 | — | — | US | disclosed |
| US-20150093339-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | FIRMENICH INCORPORATED | 2015-04-02 | — | — | US | disclosed |
| US-20150064112-A1 | USE OF T1R3 VENUS FLYTRAP REGION POLYPEPTIDE TO SCREEN FOR TASTE MODUALTORS | SENOMYX, INC. | 2015-03-05 | — | — | US | disclosed |
| US-8895050-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX, INC. (US) | 2014-11-25 | — | — | US | disclosed |
| US-8846326-B2 | — | — | 2014-09-30 | — | — | US | disclosed |
| US-8404455-B2 | Chimeric T1R taste receptor polypeptides and nucleic acid sequences encoding and cell lines that express said chimeric T1R polypeptides | SENOMYX, INC. (US) | 2013-03-26 | — | — | US | disclosed |
| US-20120201763-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX, INC. (US) | 2012-08-09 | — | — | US | disclosed |
| US-8124121-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-20110294981-A1 | CHIMERIC T1R TASTE RECEPTOR POLYPEPTIDES AND NUCLEIC ACID SEQUENCES ENCODING AND CELL LINES THAT EXPRESS SAID CHIMERIC T1R POLYPEPTIDES | FIRMENICH INCORPORATED | 2011-12-01 | — | — | US | disclosed |
| US-7888470-B2 | Chimeric T1R taste receptor polypeptides and nucleic acid sequences encoding and cell lines that express said chimeric T1R polypeptides | SENOMYX, INC. (US) | 2011-02-15 | — | — | US | disclosed |
| US-20090111834-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | SENOMYX, INC. | 2009-04-30 | — | — | US | disclosed |
| US-7476399-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-20080085994-A1 | Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli | SENOMYX, INC. | 2008-04-10 | — | — | US | disclosed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | FIRMENICH INCORPORATED | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10060909-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | TAS1R2, TAS1R1, TAS2R40 | TAS1R3 5/4885TAS1R1 2/4885SMN1; SMN2 2606/4885 |
| US-20110294981-A1 | CHIMERIC T1R TASTE RECEPTOR POLYPEPTIDES AND NUCLEIC ACID SEQUENCES ENCODING AND CELL LINES THAT EXPRESS SAID CHIMERIC T1R POLYPEPTIDES | TAS1R1, TAS1R2, TAS1R3 | TAS1R3 3/4885TAS1R1 1/4885SMN1; SMN2 2792/4885 |
| US-20150093339-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | TAS1R3 5/4885TAS1R1 2/4885SMN1; SMN2 2560/4885 |
| US-20120201763-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | TAS1R3 5/4885TAS1R1 2/4885SMN1; SMN2 2560/4885 |
| US-10352929-B2 | T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds | TAS1R2, TAS1R1, TAS2R1 | TAS1R3 4/4885TAS1R1 2/4885SMN1; SMN2 3733/4885 |
| US-20180003702-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | TAS1R2, TAS1R1, TAS2R1 | TAS1R3 4/4885TAS1R1 2/4885SMN1; SMN2 3733/4885 |
| US-20090111834-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R30 | TAS1R3 5/4885TAS1R1 2/4885SMN1; SMN2 2560/4885 |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | TAS2R40, TAS2R4, TAS2R30 | TAS1R3 17/4885TAS1R1 11/4885SMN1; SMN2 3009/4885 |
| US-20080085994-A1 | Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli | TAS1R3, TAS1R2, TAS2R30 | TAS1R3 1/4885TAS1R1 4/4885SMN1; SMN2 3772/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.