Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.42 |
| ▸ | TGM2 | P21980 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | ESR1 | P03372 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7018636 | 0.91 | MAOA (0.46) | RXFP1TGM2ALDH1A1HTTPKM | |
| SCHEMBL7016471 | 0.88 | TGM2 (0.40) | RXFP1TGM2ALDH1A1HTTPKM | |
| SCHEMBL9051500 | 0.82 | PSMB1 (0.50) | ALDH1A1KDM4EESR1 | |
| Hydrochloric Acid SCHEMBL7018187 | 0.81 | PSMB1 (0.49) | KDM4EESR1 | |
| SCHEMBL7015787 | 0.80 | MEN1 (0.51) | RXFP1ALDH1A1HTTPKMSMN1; SMN2 | |
| SCHEMBL7017587 | 0.80 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2KMT2AKDM4EMAPT | |
| SCHEMBL7015837 | 0.78 | SMN1; SMN2 (0.70) | RXFP1ALDH1A1HTTPKMSMN1; SMN2 | |
| SCHEMBL7011506 | 0.75 | MEN1 (0.55) | RXFP1ALDH1A1HTTPKMSMN1; SMN2 | |
| SCHEMBL7018169 | 0.75 | KDM4E (0.57) | ALDH1A1HTTSMN1; SMN2KMT2AMEN1 | |
| SCHEMBL7017586 | 0.73 | MEN1 (0.57) | RXFP1ALDH1A1HTTPKMSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |