Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPY1R | P25929 | 1/20 | 0.40 |
| ▸ | NPY2R | P49146 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | GFER | P55789 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012693 | 0.88 | RXFP1 (0.42) | TGM2USP2TSHRNPY1RNPY2R | |
| SCHEMBL7018636 | 0.87 | MAOA (0.46) | TGM2USP2TSHRNPY1RNPY2R | |
| SCHEMBL9051500 | 0.84 | PSMB1 (0.50) | ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL7018187 | 0.83 | PSMB1 (0.49) | KDM4E | |
| SCHEMBL7017587 | 0.82 | SMN1; SMN2 (0.44) | ALDH1A1SMN1; SMN2KDM4EMAPTKMT2A | |
| SCHEMBL7010770 | 0.82 | MEN1 (0.47) | RXFP1HTTALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL7013586 | 0.80 | SMN1; SMN2 (0.65) | RXFP1HTTALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL7011149 | 0.74 | MEN1 (0.45) | RXFP1HTTALDH1A1PKMSMN1; SMN2 | |
| SCHEMBL7013156 | 0.73 | DAO (0.50) | RXFP1HTTALDH1A1DAOPOLB | |
| SCHEMBL7011506 | 0.72 | MEN1 (0.55) | USP2RXFP1HTTALDH1A1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |