Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7012693 | 0.91 | RXFP1 (0.42) | RXFP1TGM2PKMHTTMEN1 | |
| SCHEMBL7016471 | 0.87 | TGM2 (0.40) | RXFP1TGM2PKMHTTMEN1 | |
| SCHEMBL7018169 | 0.84 | KDM4E (0.57) | MAOAMAOBLMNAHTTMEN1 | |
| SCHEMBL9051500 | 0.81 | PSMB1 (0.50) | ALDH1A1KDM4E | |
| SCHEMBL7018370 | 0.81 | MEN1 (0.50) | MAOAMAOBLMNARXFP1PKM | |
| SCHEMBL7011263 | 0.81 | MAOA (0.52) | MAOAMAOBLMNARXFP1HTT | |
| Hydrochloric Acid SCHEMBL7018187 | 0.80 | PSMB1 (0.49) | KDM4E | |
| SCHEMBL9060596 | 0.80 | MAOA (0.52) | MAOAMAOBLMNARXFP1PKM | |
| SCHEMBL7017587 | 0.80 | SMN1; SMN2 (0.44) | LMNAKMT2ARAB9AALDH1A1SMN1; SMN2 | |
| SCHEMBL7019775 | 0.79 | MEN1 (0.58) | MAOAMAOBMEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |