Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ALDH1A2 | O94788 | 4/20 | 0.36 |
| ▸ | ALDH1A3 | P47895 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | PDE1C | Q14123 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | LDHA | P00338 | 1/20 | 0.34 |
| ▸ | LDHB | P07195 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7016571 | 0.80 | MAOA (0.54) | ALDH1A1HPGDHSD17B10ALDH1A2ALDH1A3 | |
| SCHEMBL7018715 | 0.72 | TP53 (0.48) | ALDH1A1TSHRMAPK1MAPTNPSR1 | |
| SCHEMBL7012122 | 0.69 | MAOA (0.54) | ALDH1A1ALDH1A2ALDH1A3TSHRMAPT | |
| SCHEMBL8005250 | 0.66 | MAPK1 (0.50) | ALDH1A1HPGDTSHRMAPK1MAPT | |
| SCHEMBL7019301 | 0.65 | TP53 (0.45) | ALDH1A1HSD17B10TSHRMAPK1MAPT | |
| SCHEMBL7011645 | 0.65 | ALDH1A1 (0.58) | ALDH1A1HSD17B10ALDH1A2ALDH1A3TSHR | |
| SCHEMBL7019303 | 0.63 | TP53 (0.46) | ALDH1A1TSHRMAPK1MAPTNPSR1 | |
| SCHEMBL7014404 | 0.63 | TP53 (0.46) | ALDH1A1HSD17B10TSHRMAPK1MAPT | |
| SCHEMBL3151943 | 0.63 | CNR1 (0.60) | ALDH1A1HPGDTSHRMAPK1MAPT | |
| SCHEMBL7011866 | 0.63 | MAOA (0.46) | ALDH1A1HPGDHSD17B10TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |