Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 6/20 | 1.00 |
| ▸ | TAS1R1 | Q7RTX1 | 6/20 | 1.00 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.70 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.70 |
| ▸ | GAA | P10253 | 1/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.70 |
| ▸ | LMNA | P02545 | 2/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | TAS1R2 | Q8TE23 | 4/20 | 0.65 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.61 |
| ▸ | ATM | Q13315 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL703637 | 0.85 | TAS1R3 (1.00) | TAS1R3TAS1R1NPSR1ALDH1A1KDM4E | |
| SCHEMBL701934 | 0.79 | TAS1R3 (1.00) | TAS1R3TAS1R1ALDH1A1LMNAKMT2A | |
| SCHEMBL5122807 | 0.79 | ALDH1A1 (0.65) | TAS1R3TAS1R1NPSR1ALDH1A1KDM4E | |
| SCHEMBL11746591 | 0.78 | KMT2A (0.70) | TAS1R3TAS1R1NPSR1ALDH1A1KDM4E | |
| SCHEMBL11746602 | 0.78 | KMT2A (0.70) | TAS1R3TAS1R1NPSR1ALDH1A1KDM4E | |
| SCHEMBL701855 | 0.78 | TAS1R3 (1.00) | TAS1R3TAS1R1ALDH1A1KMT2AMEN1 | |
| SCHEMBL701854 | 0.78 | TAS1R3 (1.00) | TAS1R3TAS1R1ALDH1A1KMT2AMEN1 | |
| SCHEMBL13007504 | 0.77 | KMT2A (0.68) | TAS1R3TAS1R1NPSR1ALDH1A1KDM4E | |
| Hydrochloric Acid SCHEMBL11745237 | 0.77 | KMT2A (0.68) | TAS1R3TAS1R1NPSR1ALDH1A1KDM4E | |
| SCHEMBL702936 | 0.77 | TAS1R3 (1.00) | TAS1R3TAS1R1ALDH1A1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11268952-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | FIRMENICH INCORPORATED (US) | 2022-03-08 | — | — | US | disclosed |
| US-11268952-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | FIRMENICH INCORPORATED (US) | 2022-03-08 | — | — | US | disclosed |
| US-20200225217-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | FIRMENICH INCORPORATED (US) | 2020-07-16 | — | — | US | disclosed |
| US-20200225217-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | FIRMENICH INCORPORATED (US) | 2020-07-16 | — | — | US | disclosed |
| US-20200049699-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | SENOMYX, INC. | 2020-02-13 | — | — | US | disclosed |
| US-10557845-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | FIRMENICH INCORPORATED (US) | 2020-02-11 | — | — | US | disclosed |
| US-10557845-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | FIRMENICH INCORPORATED (US) | 2020-02-11 | — | — | US | disclosed |
| US-10352929-B2 | T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds | SENOMYX, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| US-10352929-B2 | T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds | SENOMYX, INC. (US) | 2019-07-16 | — | — | US | disclosed |
| EP-3431464-A2 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | Senomyx Inc. (US) | 2019-01-23 | — | — | EP | disclosed |
| US-7476399-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-7476399-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-7476399-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | SENOMYX INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-20080085994-A1 | Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli | SENOMYX, INC. | 2008-04-10 | — | — | US | disclosed |
| US-20080085994-A1 | Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli | SENOMYX, INC. | 2008-04-10 | — | — | US | disclosed |
| US-20080085994-A1 | Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli | SENOMYX, INC. | 2008-04-10 | — | — | US | disclosed |
| US-20070104709-A1 | Non-naturally occurring ligand for umami taste and sweet taste receptor; enhancing response to artificial flavoring | FIRMENICH INCORPORATED | 2007-05-10 | — | — | US | disclosed |
| US-20070104709-A1 | Non-naturally occurring ligand for umami taste and sweet taste receptor; enhancing response to artificial flavoring | FIRMENICH INCORPORATED | 2007-05-10 | — | — | US | disclosed |
| US-20060045953-A1 | Aromatic amides and ureas and their uses as sweet and/or umami flavor modifiers, tastants and taste enhancers | SENOMYX, INC. | 2006-03-02 | — | — | US | disclosed |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | FIRMENICH INCORPORATED | 2005-04-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200049699-A1 | T1R HETERO-OLIGOMERIC TASTE RECEPTORS, CELL LINES THAT EXPRESS SAID RECEPTORS, AND TASTE COMPOUNDS | TAS1R2, TAS1R1, TAS2R1 | TAS1R3 4/4885TAS1R1 2/4885NPSR1 175/4885 |
| US-20200225217-A1 | NOVEL FLAVORS, FLAVOR MODIFIERS, TASTANTS, TASTE ENHANCERS, UMAMI OR SWEET TASTANTS, AND/OR ENHANCERS AND USE THEREOF | TAS1R2, TAS1R1, TAS2R40 | TAS1R3 5/4885TAS1R1 2/4885NPSR1 726/4885 |
| US-10557845-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | TAS1R2, TAS1R1, TAS2R40 | TAS1R3 5/4885TAS1R1 2/4885NPSR1 862/4885 |
| US-10352929-B2 | T1R hetero-oligomeric taste receptors, cell lines that express said receptors, and taste compounds | TAS1R2, TAS1R1, TAS2R1 | TAS1R3 4/4885TAS1R1 2/4885NPSR1 175/4885 |
| US-11268952-B2 | Flavors, flavor modifiers, tastants, taste enhancers, umami or sweet tastants, and/or enhancers and use thereof | TAS2R40, TAS1R2, TAS1R1 | TAS1R3 5/4885TAS1R1 3/4885NPSR1 800/4885 |
| US-20050084506-A1 | Amide compounds such as (R)-methyl 2-(3-chloro-4-methoxybenzamido)-4-methylpentanoate and urea compounds such as 1-(2-chlorophenyl)-3-(heptan-4-yl)urea for modulating taste of food or drug products | TAS2R40, TAS2R4, TAS2R30 | TAS1R3 17/4885TAS1R1 11/4885NPSR1 1922/4885 |
| US-20070104709-A1 | Non-naturally occurring ligand for umami taste and sweet taste receptor; enhancing response to artificial flavoring | TAS1R2, TAS1R3, TAS2R30 | TAS1R3 2/4885TAS1R1 4/4885NPSR1 182/4885 |
| US-20080085994-A1 | Chimeric binding protein for use in identifying compounds which respond to umami taste stimuli and sweet taste stimuli | TAS1R3, TAS1R2, TAS2R30 | TAS1R3 1/4885TAS1R1 4/4885NPSR1 422/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.