Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | CTSD | P07339 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MITF | O75030 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7560618 | 0.84 | TSHR (0.46) | LMNAALDH1A1MAPTCYP3A4KMT2A | |
| SCHEMBL6070445 | 0.78 | SIRT6 (0.43) | LMNAALDH1A1MAPTCYP3A4BLM | |
| SCHEMBL28683195 | 0.77 | TSHR (0.34) | LMNAALDH1A1MAPTCYP3A4KMT2A | |
| SCHEMBL29287448 | 0.75 | MAPT (0.38) | ALDH1A1MAPTCYP3A4BLMPMP22 | |
| SCHEMBL1028967 | 0.75 | TDP1 (0.50) | LMNAALDH1A1MAPTCYP3A4KMT2A | |
| SCHEMBL57882 | 0.74 | TSHR (0.40) | ALDH1A1MAPTCYP3A4KMT2ATSHR | |
| SCHEMBL12970754 | 0.74 | ALDH1A1 (0.38) | ALDH1A1MAPTCYP3A4BLMPMP22 | |
| SCHEMBL115478 | 0.73 | CTSD (0.65) | LMNAALDH1A1MAPTCYP3A4KMT2A | |
| SCHEMBL1028675 | 0.73 | GPR35 (0.47) | LMNAALDH1A1MAPTCYP3A4PMP22 | |
| SCHEMBL2783828 | 0.73 | TDP1 (0.48) | LMNAALDH1A1MAPTCYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1345888-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | Bayer Aktiengesellschaft (DE) | 2003-09-24 | — | — | EP | disclosed |
| WO-2002051792-A1 | METHOD FOR THE PRODUCTION OF 1,5-NAPHTHALENEDIAMINE | BAYER AKTIENGESELLSCHAFT (DE) | 2002-07-04 | — | — | WO | disclosed |