Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CASP6 | P55212 | 2/20 | 0.46 |
| ▸ | DTYMK | P23919 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | DNA2 | P51530 | 1/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MYC | P01106 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL246196 | 0.85 | DTYMK (0.49) | TSHRLMNACASP6DTYMKPOLB | |
| SCHEMBL7013577 | 0.84 | LMNA (0.44) | TSHRLMNACASP6POLBTDP1 | |
| SCHEMBL6070445 | 0.80 | SIRT6 (0.43) | TSHRLMNAPOLBTDP1ALDH1A1 | |
| SCHEMBL28683195 | 0.79 | TSHR (0.34) | TSHRLMNACASP6TDP1ALDH1A1 | |
| SCHEMBL57882 | 0.76 | TSHR (0.40) | TSHRCASP6POLBTDP1ALDH1A1 | |
| SCHEMBL1028675 | 0.75 | GPR35 (0.47) | TSHRLMNATDP1ALDH1A1CYP3A4 | |
| SCHEMBL6800906 | 0.74 | TDP1 (0.38) | TSHRPOLBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL490677 | 0.73 | ALDH1A1 (0.48) | TSHRPOLBTDP1ALDH1A1ALOX15 | |
| SCHEMBL6197923 | 0.72 | KDM4E (0.44) | CASP6POLBTDP1ALDH1A1CYP3A4 | |
| SCHEMBL1028967 | 0.72 | TDP1 (0.50) | TSHRLMNAPOLBTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2002005616-A1 | NOVEL 6-PHENYLPHENANTHRIDINES | ALTANA PHARMA AG (DE) | 2002-01-24 | — | — | WO | disclosed |