Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | APP | P05067 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10943823 | 0.82 | TSHR (0.39) | TSHRALDH1A1MAPT | |
| Ethylenediamine SCHEMBL9516578 | 0.78 | MEN1 (0.41) | TSHRMAPK1MEN1KMT2ATHRB | |
| SCHEMBL10934843 | 0.76 | ALDH1A1 (0.32) | TSHRALDH1A1 | |
| SCHEMBL9396104 | 0.73 | NOS3 (0.43) | TSHRMEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL27575810 | 0.73 | TSHR (0.56) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL2139314 | 0.71 | NFKB1 (0.52) | TSHR | |
| Di(Hydroxyethyl)Ether SCHEMBL28229831 | 0.71 | TSHR (0.53) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| SCHEMBL5153189 | 0.70 | THRB (0.47) | TSHRALDH1A1THRBHTT | |
| Di(Hydroxyethyl)Ether SCHEMBL11797711 | 0.70 | TSHR (0.67) | TSHRMAPK1MEN1KMT2AALDH1A1 | |
| Di(Hydroxyethyl)Ether SCHEMBL9191605 | 0.70 | TSHR (0.67) | TSHRMAPK1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017665-B1 | COMPOSITIONS COMPRISING ALUMINIUM ACETOACETATE COMPOUNDS, THE PRODUCTION AND USE THEREOF AS PRINTING INK ADDITIVES | SASOL GERMANY GMBH (DE) | 2003-01-08 | — | — | EP | disclosed |
| EP-1017665-A1 | ALUMINIUM ACETOACETATE COMPOUNDS, THE PRODUCTION AND USE THEREOF AS PRINTING INK ADDITIVES | RWE-DEA AKTIENGESELLSCHAFT FÜR MINERALOEL UND CHEMIE (DE) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999016739-A1 | ALUMINIUM ACETOACETATE COMPOUNDS, THE PRODUCTION AND USE THEREOF AS PRINTING INK ADDITIVES | RWE-DEA Aktiengesellschaft für Mineraloel und Chemie (DE) | 1999-04-08 | — | — | WO | disclosed |