Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 6/20 | 0.48 |
| ▸ | TUBB4A | P04350 | 4/20 | 0.48 |
| ▸ | TUBB | P07437 | 4/20 | 0.48 |
| ▸ | TUBA3C | P0DPH7 | 4/20 | 0.48 |
| ▸ | TUBA1B | P68363 | 4/20 | 0.48 |
| ▸ | TUBA4A | P68366 | 4/20 | 0.48 |
| ▸ | TUBB4B | P68371 | 4/20 | 0.48 |
| ▸ | TUBB3 | Q13509 | 4/20 | 0.48 |
| ▸ | TUBB2A | Q13885 | 4/20 | 0.48 |
| ▸ | TUBB8 | Q3ZCM7 | 4/20 | 0.48 |
| ▸ | TUBA3E | Q6PEY2 | 4/20 | 0.48 |
| ▸ | TUBA1A | Q71U36 | 4/20 | 0.48 |
| ▸ | TUBA1C | Q9BQE3 | 4/20 | 0.48 |
| ▸ | TUBB6 | Q9BUF5 | 4/20 | 0.48 |
| ▸ | TUBB2B | Q9BVA1 | 4/20 | 0.48 |
| ▸ | TUBB1 | Q9H4B7 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7019933 | 0.85 | HDAC1 (0.41) | HDAC6HDAC1HDAC2HDAC4MAPT | |
| SCHEMBL7017888 | 0.85 | TP53 (0.47) | HDAC6HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL7010029 | 0.80 | TP53 (0.36) | HDAC6HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL7016306 | 0.79 | TP53 (0.35) | HDAC6HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL7014404 | 0.78 | TP53 (0.46) | HDAC6HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL7010027 | 0.76 | TP53 (0.35) | HDAC6HDAC1HDAC4MAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL7012711 | 0.76 | PSMB1 (0.49) | MAPTALDH1A1KDM4ETSHR | |
| SCHEMBL7019303 | 0.76 | TP53 (0.46) | HDAC6HDAC1HDAC2HDAC8HDAC3 | |
| SCHEMBL7015187 | 0.75 | RAB9A (0.37) | HDAC1HDAC2MAPTALDH1A1GAA | |
| Hydrochloric Acid SCHEMBL7016878 | 0.75 | SRC (0.39) | MAPTALDH1A1KMT2AKDM4ETSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0733633-B1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 2003-05-28 | — | — | EP | disclosed |
| EP-0733633-A1 | Heterocyclic compounds, their production and use | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1996-09-25 | — | — | EP | disclosed |