SCHEMBL701634

SCHEMBL701634

[NH]C(=O)c1ccccc1CCl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.39
TSHR P16473 4/20 0.39
FOLH1 Q04609 1/20 0.38
ALOX15 P16050 2/20 0.37
CES2 O00748 1/20 0.37
CES1 P23141 1/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
HPGD P15428 3/20 0.35
TRPA1 O75762 1/20 0.35
MAPK1 P28482 1/20 0.35
GSK3B P49841 1/20 0.35
HIF1A Q16665 1/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPT P10636 1/20 0.35
HSD17B10 Q99714 1/20 0.35
HTT P42858 2/20 0.35
TP53 P04637 1/20 0.35
CASP3 P42574 1/20 0.35
SENP8 Q96LD8 1/20 0.35
SENP7 Q9BQF6 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3145510 0.82 ALDH1A1 (0.42) ALDH1A1TSHRFOLH1ALOX15CES2
SCHEMBL152624 0.80 ALDH1A1 (0.50) ALDH1A1TSHRFOLH1ALOX15CES2
SCHEMBL602386 0.80 FOLH1 (0.59) ALDH1A1TSHRFOLH1ALOX15HPGD
SCHEMBL873231 0.80 HPGD (0.52) ALDH1A1TSHRFOLH1ALOX15L3MBTL1
SCHEMBL4261085 0.80 GABRA1 (0.44) ALDH1A1TSHRFOLH1L3MBTL1HPGD
SCHEMBL1004137 0.78 KDM4E (0.50) ALDH1A1TSHRL3MBTL1HPGDKDM4E
Hydrochloric Acid SCHEMBL3624217 0.78 FOLH1 (0.57) ALDH1A1TSHRFOLH1ALOX15HPGD
SCHEMBL11359573 0.78 ALDH1A1 (0.39) ALDH1A1TSHRFOLH1ALOX15CES2
SCHEMBL11754245 0.78 FOLH1 (0.42) ALDH1A1TSHRFOLH1ALOX15CES2
SCHEMBL11721016 0.78 ALDH1A1 (0.50) ALDH1A1TSHRFOLH1ALOX15CES2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8729307-B2 Photoresponsive ionic organic compound, method of producing the same, and photoresponsive carbon nanotube dispersant comprising said ionic organic compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2014-05-20 US claimed
US-20120217151-A1 PHOTORESPONSIVE IONIC ORGANIC COMPOUND, METHOD OF PRODUCING THE SAME, AND PHOTORESPONSIVE CARBON NANOTUBE DISPERSANT COMPRISING SAID IONIC ORGANIC COMPOUND NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2012-08-30 US claimed
US-6004536-A USED FOR STAINING MEMBRANES IN CELLS OR ISOLATED FROM CELLS, ARE WELL-RETAINED THEREIN MOLECULAR PROBES, INC. (US) 1999-12-21 US claimed
CN-113207298-B Technique for preparing myocardial cell aggregate for improving survival rate under freezing preservation and hypoxia condition T&R碧欧法博有限公司 2024-05-28 CN disclosed
US-20220119769-A1 FABRICATION TECHNIQUE FOR CARDIOMYOCYTE CLUSTER WITH IMPROVED VIABILITY IN CRYOPRESERVATION AND HYPOXIC CONDITION T&R BIOFAB CO., LTD. (KR) 2022-04-21 US disclosed
WO-2021112374-A1 CARDIOMYOCYTE AGGREGATE PRODUCTION TECHNIQUE IMPROVING SURVIVAL RATE UNDER CRYOPRESERVATION AND HYPOXIC CONDITIONS 주식회사 티앤알바이오팹 2021-06-10 WO disclosed
US-8729307-B2 Photoresponsive ionic organic compound, method of producing the same, and photoresponsive carbon nanotube dispersant comprising said ionic organic compound NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2014-05-20 US disclosed
US-8535941-B2 Lipophilic dye-based FRET assays for clostridial toxin activity ALLERGAN, INC. (US) 2013-09-17 US disclosed
US-20120231538-A1 LIPOPHILIC DYE-BASED FRET ASSAYS FOR CLOSTRIDIAL TOXIN ACTIVITY ALLERGAN, INC. (US) 2012-09-13 US disclosed
US-20120217151-A1 PHOTORESPONSIVE IONIC ORGANIC COMPOUND, METHOD OF PRODUCING THE SAME, AND PHOTORESPONSIVE CARBON NANOTUBE DISPERSANT COMPRISING SAID IONIC ORGANIC COMPOUND NATIONAL INSTITUTE OF ADVANCED INDUSTRIAL SCIENCE AND TECHNOLOGY (JP) 2012-08-30 US disclosed
US-8124357-B2 Cell comprising exogenous clostridial toxin receptor for use as quality control agents in pharmaceutical and food processing ALLERGAN, INC. (US) 2012-02-28 US disclosed
EP-2293064-A1 Lipophilic dye-based FRET assays for clostridial toxin activity ALLERGAN, INC. (US) 2011-03-09 EP disclosed
EP-1869459-B1 LIPOPHILIC DYE-BASED FRET ASSAYS FOR CLOSTRIDIAL TOXIN ACTIVITY ALLERGAN INC (US) 2010-06-09 EP disclosed
US-20080160561-A1 Lipophilic Dye-Based Fret Assays for Clostridal Toxin Activity ALLERGAN INC. (US) 2008-07-03 US disclosed
EP-1869459-A2 LIPOPHILIC DYE-BASED FRET ASSAYS FOR CLOSTRIDIAL TOXIN ACTIVITY Allergan, Inc. (US) 2007-12-26 EP disclosed
EP-1843160-A1 Simultaneous determination of forward and reverse abo blood group ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2007-10-10 EP disclosed
WO-2006107921-A2 LIPOPHILIC DYE-BASED FRET ASSAYS FOR CLOSTRIDIAL TOXIN ACTIVITY ALLERGAN, INC. (US) 2006-10-12 WO disclosed
US-6955889-B1 Simultaneous determination of forward and reverse ABO blood group ORTHO-CLINICAL DIAGNOSTICS, INC. (US) 2005-10-18 US disclosed
EP-1059534-A2 Simultaneous determination of forward and reverse ABO blood group Ortho-Clinical Diagnostics, Inc. (US) 2000-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120217151-A1 PHOTORESPONSIVE IONIC ORGANIC COMPOUND, METHOD OF PRODUCING THE SAME, AND PHOTORESPONSIVE CARBON NANOTUBE DISPERSANT COMPRISING SAID IONIC ORGANIC COMPOUND CNTN1, CRY2, CRY1 ALDH1A1 1651/4885TSHR 2785/4885FOLH1 4855/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.