Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A3 | P47895 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.35 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | AOX1 | Q06278 | 1/20 | 0.34 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.34 |
| ▸ | ABAT | P80404 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3233108 | 0.80 | ALDH1A3 (0.46) | ALDH1A3ALDH1A1ALDH3A1TSHRRAB9A | |
| SCHEMBL30228794 | 0.78 | L3MBTL1 (0.55) | ALDH1A3ALDH1A1TSHRRAB9AKDM4E | |
| SCHEMBL6364244 | 0.78 | L3MBTL1 (0.55) | ALDH1A3ALDH1A1TSHRRAB9AKDM4E | |
| SCHEMBL29399275 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRRAB9AKDM4EPTGS2 | |
| SCHEMBL2395571 | 0.77 | ALDH1A1 (0.55) | ALDH1A3ALDH1A1ALDH3A1TSHRRAB9A | |
| SCHEMBL48553 | 0.77 | ALDH1A1 (0.42) | ALDH1A1TSHRRAB9AKDM4EPTGS2 | |
| SCHEMBL2393712 | 0.77 | KIF11 (0.42) | ALDH1A1TSHRL3MBTL1PIK3CDPIK3CA | |
| SCHEMBL7022248 | 0.76 | TDP1 (0.46) | ALDH1A1KDM4EPTGS2L3MBTL1PIK3CD | |
| SCHEMBL25229335 | 0.76 | ALDH1A1 (0.53) | ALDH1A3ALDH1A1ALDH3A1TSHRRAB9A | |
| SCHEMBL2646368 | 0.75 | HSP90AA1 (0.43) | ALDH1A1L3MBTL1PIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1091933-B1 | SUBSTITUTED BETA-DIKETONES AND THEIR USE | ORION CORP (FI) | 2003-11-26 | — | — | EP | claimed |
| EP-1091933-A1 | SUBSTITUTED $g(b)-DIKETONES AND THEIR USE | ORION CORPORATION (FI) | 2001-04-18 | — | — | EP | claimed |
| WO-2000001667-A1 | SUBSTITUTED β-DIKETONES AND THEIR USE | ORION CORPORATION (FI) | 2000-01-13 | — | — | WO | claimed |
| EP-1091933-B1 | SUBSTITUTED BETA-DIKETONES AND THEIR USE | ORION CORP (FI) | 2003-11-26 | — | — | EP | disclosed |
| EP-1091933-A1 | SUBSTITUTED $g(b)-DIKETONES AND THEIR USE | ORION CORPORATION (FI) | 2001-04-18 | — | — | EP | disclosed |
| US-6201027-B1 | NONSTEROIDAL ANTIINFLAMMATORY DRUG FOR PROPHYLAXIS AND TREATMENT OF RESPIRATORY SYSTEM DISORDERS, I.E. ASTHMA, IN STEROID-RESISTANT MAMMALS | ORION CORPORATION (FI) | 2001-03-13 | — | — | US | disclosed |
| WO-2000001667-A1 | SUBSTITUTED β-DIKETONES AND THEIR USE | ORION CORPORATION (FI) | 2000-01-13 | — | — | WO | disclosed |